Cluster-randomized trial of monthly malaria prophylaxis versus focused screening and treatment: a study protocol to define malaria elimination strategies in Cambodia
DiscussionDespite the apparent urgency, the key operational elements of proposed malaria elimination strategies in Southeast Asian mobile and migrant populations, including the Military, have yet to be rigorously tested in a well-controlled clinical study. Here, we present a protocol for the primary evaluation of two treatment paradigms – monthly malaria prophylaxis and focused screening and treatment – to achieve malaria elimination in a Cambodian military population. We will also assess the feasibility and incremental benefit of outdoor-biting vector intervention – permethrin-treated clothing. In the process, we ai...
Source: Trials - October 16, 2018 Category: Research Source Type: clinical trials

Safety and Efficacy of Different Regimens of Primaquine on Vivax Malaria Treatment in G6PD Deficient Patients
Conditions:   Vivax Malaria;   G6PD Deficiency Interventions:   Drug: Chloroquine;   Drug: Primaquine Sponsors:   Fundação de Medicina Tropical Dr. Heitor Vieira Dourado;   Oswaldo Cruz Foundation;   Conselho Nacional de Desenvolvimento Científico e Tecnológico Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 18, 2018 Category: Research Source Type: clinical trials