Pragmatic cluster-randomized trial of home-based preventive treatment for TB in Ethiopia and South Africa (CHIP-TB)
In this study, we aim to evaluate the effectiveness and cost-effectiveness of home-based contact management with TPT initiation in two TB high-burden African countries, Ethiopia and South Africa.MethodsThis pragmatic cluster randomized trial compares home-based versus facility-based care delivery models for contact management. Thirty-six clinics with decentralized TB services (18 in Ethiopia and 18 in South Africa) were randomized in a 1:1 ratio to conduct either home-based or facility-based contact management. The study will attempt to enroll all eligible close child contacts of infectious drug-sensitive TB index patients...
Source: Trials - July 25, 2023 Category: Research Source Type: clinical trials

LXE408 for Treatment of Visceral Leishmaniasis in Ethiopia, a Proof of Concept Study
Condition:   Primary Visceral Leishmaniasis Interventions:   Drug: LXE408;   Drug: sodium stibogluconate;   Drug: Paromomycin Sponsors:   Drugs for Neglected Diseases;   Novartis Pharmaceuticals Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - July 24, 2023 Category: Research Source Type: clinical trials

Addressing Stress Among Women Entrepreneurs in Ethiopia - Scale up
Conditions:   Mental Stress;   Stress;   Stress, Job;   Emotion Regulation;   Violence, Gender-Based;   Economic Problems Intervention:   Behavioral: Stress managment Sponsors:   World Bank;   Ethiopian Medical Association;   Policy Studies Institute;   Addis Ababa University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 5, 2023 Category: Research Source Type: clinical trials