Low-Dose Doxycycline May Slow Diabetic RetinopathyLow-Dose Doxycycline May Slow Diabetic Retinopathy
Researchers say the observation suggests a link between a low-dose oral anti-inflammatory agent and subclinical improvement in inner retinal function. Medscape Medical News (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - March 14, 2014 Category: Consumer Health News Tags: Ophthalmology News Source Type: news
Doctors issue new treatment guidelines for skin abscesses caused by MRSA
It has been more than 10 years since the clinical battle began with community-acquired methicillin-resistant Staphylococcus aureus (MRSA), and doctors are still grappling with how to diagnose, treat and prevent this virulent form of staph infection, which is immune to many antibiotics.
As MRSA cases have increased dramatically over the decade, so have the number of skin abscesses — generally pus-filled boils or pimples with discharge — that characterize these infections. Now, researchers from UCLA have issued updated guidelines outlining the best ways to treat and manage these abscesses.
The ...
Source: UCLA Newsroom: Health Sciences - March 12, 2014 Category: Universities & Medical Training Source Type: news
Doctors issue new treatment guidelines for skin abscesses caused by MRSA
It has been more than 10 years since the clinical battle began with community-acquired methicillin-resistant Staphylococcus aureus (MRSA), and doctors are still grappling with how to diagnose, treat and prevent this virulent form of staph infection, which is immune to many antibiotics. As MRSA cases have increased dramatically over the decade, so have the number of skin abscesses — generally pus-filled boils or pimples with discharge — that characterize these infections. Now, researchers from UCLA have issued updated guidelines outlining the best ways to treat and manage these abscesses. The first cases of MRSA were ...
Source: UCLA Newsroom: Health Sciences - March 12, 2014 Category: Universities & Medical Training Source Type: news
Featured in NEJM Journal Watch: Lack of Efficacy for Doxycycline in Stunting Aneurysm Growth (FREE)
By the NEJM Journal Watch Editors
Contrary to evidence from preclinical studies, doxycycline failed … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - January 27, 2014 Category: Primary Care Source Type: news
Doxycycline and suicidality - Atigari OV, Hogan C, Healy D.
A case series outlining three young individuals with no history of mental disorder who were treated for skin conditions with doxycycline, but developed suicidal ideation with an outcome of suicide in two of the cases. One of these individuals had CYP2C19*2... (Source: SafetyLit: All (Unduplicated))
Source: SafetyLit: All (Unduplicated) - December 25, 2013 Category: Global & Universal Tags: Suicide and Self-Harm Source Type: news
Treatment of Infections Due to Resistant Staphylococcus aureus
This chapter reviews data on the treatment of infections caused by drug-resistant Staphylococcus aureus, particularly methicillin-resistant S. aureus (MRSA). This review covers findings reported in the English language medical literature up to January of 2013. Despite the emergence of resistant and multidrug-resistant S. aureus, we have seven effective drugs in clinical use for which little resistance has been observed: vancomycin, quinupristin–dalfopristin, linezolid, tigecycline, telavancin, ceftaroline, and daptomycin. However, vancomycin is less effective for infections with MRSA isolates that have a higher MIC w...
Source: Springer protocols feed by Microbiology - October 6, 2013 Category: Microbiology Source Type: news
Lupin receives tentative FDA approvals for generic Nuvigil tablets and generic Oracea capsules
elsPharma Major Lupin Limited has announced that its U.S. subsidiary, Lupin Pharmaceuticals, Inc. (LPI) has received tentative approval for its Armodafinil Tablets, 50 mg, 100 mg, 150 mg, 200 mg and 250 mg strengths as well as another tentative approval for its Doxycycline Capsules, 40 mg (30 mg Immediate-release and 10 mg Delayed-release) from the United States Food and Drugs Administration (FDA). Lupin's Armodafinil Tablets are the AB-rated generic equivalent of Cephalon Inc's Nuvigil(R) tablets 50 mg, 100 mg, 150 mg, 200 mg and 250 mg strengths... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - August 2, 2013 Category: Consumer Health News Tags: Regulatory Affairs / Drug Approvals Source Type: news
CDC: Cut Back on Doxycycline Use
(MedPage Today) -- A continuing shortage of doxycycline means the drug should be used only for conditions that have no alternative treatments, the CDC advised this week. (Source: MedPage Today Pediatrics)
Source: MedPage Today Pediatrics - June 14, 2013 Category: Pediatrics Source Type: news
Prescription needed to remedy generic drug pricing shenanigans
Prices for generic prescription drugs can often go on a roller coaster. The FDA should take action to help consumers find out the true cost of such medicine.Wanda Ferrin fills her husband's prescription for the generic antibiotic doxycycline at a Target in Simi Valley. For years, the medication has cost her $6 a month. (Source: L.A. Times - Health)
Source: L.A. Times - Health - March 19, 2013 Category: Consumer Health News Source Type: news
When a drug costs 30 times what it once did
Manufacturers can charge wildly different prices for essentially the same generic medicine. Pharmacies should make clear whether a customer is getting the lowest-priced generic available.Diane Shattuck filled a prescription in December for a generic antibiotic called doxycycline. With insurance, she paid $4.30 for 60 pills at a CVS store in Orange. (Source: L.A. Times - Health)
Source: L.A. Times - Health - March 8, 2013 Category: Consumer Health News Source Type: news
Extrachromosomal Inducible Expression
Inducible expression systems are very convenient for proteins that induce strong side effects such as retardation of growth or development and are essential for the expression of toxic proteins. In this chapter we describe the doxycycline-inducible expression system, optimized for the controlled expression in. Two types of inducible plasmids are presented, in which transcription is induced by either adding or removing doxycycline, respectively. Detailed protocols are provided for the construction of the plasmids and the inducible expression of the target protein. (Source: Springer protocols feed by Microbiology)
Source: Springer protocols feed by Microbiology - March 6, 2013 Category: Microbiology Source Type: news
Go For The Glory Quiz: Down Syndrome Complications, Infant Shock, Stroke Survivors, Doxycycline Adverse Events
Go For The Glory Quiz: Test your skills in this week's 5-question quiz. (Source: Consultant Live)
Source: Consultant Live - February 28, 2013 Category: Primary Care Source Type: news
Target Validation in Mice by Constitutive and Conditional RNAi
We describe three strategies to control gene silencing in mice that can be applied to any transcript of interest. This shRNA based approach enables either i) constitutive body-wide knockdown, ii) cell type-specific knockdown controlled by Cre recombinase, or iii) inducible body-wide knockdown controlled by doxycycline. For reliable expression the shRNA vector of interest is inserted into a Rosa26 docking site of ES cells by a site-specific recombinase. These ES cells can then be used to generate shRNA transgenic mice. This technology enables the production of adult knockdown mice within 11 months for an expedite in vivo va...
Source: Springer protocols feed by Pharmacology/Toxicology - February 26, 2013 Category: Drugs & Pharmacology Source Type: news
Fixed Drug Eruption
A 41-year-old man was treated with doxycycline for non-gonococcal urethritis. Five days into his therapy, a superficial but painful neck lesion developed. (Source: Consultant Live)
Source: Consultant Live - January 17, 2013 Category: Primary Care Source Type: news
Haiti
the Major disasters in the last 10 years, 2000 – 2010:
2001 – Gujarat Earthquake, India 20,000 Deaths
2003 – Bam Earthquake, Iran 30,000 Deaths
2004 – Indian Ocean Earthquake and Tsunami 230,000 Deaths
2005 – Kashmir Earthquake, Pakistan 85,000 Deaths
2005 – Hurricane Katrina, USA 1,300 Deaths
2008 – Sichuan China Earthquake, Chine 70,000 Deaths
200...
Source: Wilderness Medicine Newsletter - February 5, 2010 Category: Rural Health Authors: wildernessmedicinenewsletter Tags: Disaster Medicine Emergency Medicine Environmental Emergencies wilderness emergency medicine Wilderness Medicine wilderness medicine newsletter Earthquake Haiti Earthquake response resuers in Haiti Source Type: news
