Randomized control trial of prednisolone and doxycycline in patients with acute interstitial nephritis of unknown aetiology
ConclusionPrednisolone and doxycycline were not beneficial for the earliest presentation of CKDu at 6 months. However, there is a potential benefit of prednisolone on the long-term outcome of CKDu. An adequately powered steroid trial using patients reaching < 30 ml/min/1.73m2 eGFR by 3 years, as an outcome is warranted for AIN of unknown aetiology.Trial registrationSri Lanka Clinical Trial Registry SLCTR/2014/007, Registered on the 31st of March 2014. (Source: Trials)
Source: Trials - January 5, 2023 Category: Research Source Type: clinical trials
Ocular Rosacea microBiome Study (ORBS) —sub-microbial versus antibiotic dosing of doxycycline versus placebo in treatment of symptomatic ocular rosacea: study protocol for a parallel-arm randomized clinical trial
DiscussionThese results will enhance our understanding of the overall systemic impact of long-term systemic sub-microbial antibiotic dosing for the treatment of chronic recurrent ocular inflammatory diseases.Trial registrationThis trial was registered on ClinicalTrials.org (NCT05296837) on March 22, 2022. (Source: Trials)
Source: Trials - December 20, 2022 Category: Research Source Type: clinical trials
Comparison Of Doxycycline And Common Salt For Treatment Of Umbilical Granuloma: A Randomised Control Trial
Condition: Umbilical Granuloma Interventions: Drug: Doxycyclin; Other: COMMON SALT Sponsor: Shaheed Zulfiqar Ali Bhutto Medical University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 19, 2022 Category: Research Source Type: clinical trials
