Ketamine Versus Propofol as ICU Sedation
Conditions: Ketamine; Propofol; Sedation; Mechanical Ventilation Interventions: Drug: Ketamine; Drug: Propofol Sponsors: Menoufia University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 6, 2024 Category: Research Source Type: clinical trials

Effect of remimazolam vs propofol in high-risk patients undergoing upper gastrointestinal endoscopy: a non-inferiority randomized controlled trial
DiscussionThis trial aims to determine whether remimazolam is non-inferior to propofol for procedural sedation during upper gastrointestinal endoscopy in high-risk patients, regarding success rate, complication incidence, patient comfort, and satisfaction.Trial registration {2a and 2b}Chinese Clinical Trial Registry ClinicalTrials.gov ChiCTR2200066527. Registered on 7 December 2022. (Source: Trials)
Source: Trials - January 27, 2024 Category: Research Source Type: clinical trials

EEG-guided Propofol Sedation Versus Standard Care for Oesophagogastroduodenoscopy and Colonoscopy in Children
Conditions: Anesthesia; Anesthesia; Adverse Effect; Anesthesia Emergence Delirium; Sedation Complication; Sedative Adverse Reaction Interventions: Device: Sedline EEG monitoring; Device: Sedline EEG with output concealed Sponsors: KK Women ' s and Children ' s Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 25, 2024 Category: Research Source Type: clinical trials

A Study of Remimazolam Tosilate for Sedation in the ICU
Conditions: Sedation in the ICU Interventions: Drug: Remimazolam Tosilate; Drug: Propofol Medium and Long Chain Fat Emulsion Injection Sponsors: Jiangsu HengRui Medicine Co., Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 24, 2024 Category: Research Source Type: clinical trials

Efficacy of Low Dose Propofol Given at the End of Sevoflurane Anesthesia for Prevention of Emergence Agitation in Pediatric Patient Undergoing MRI Scan
Conditions: Emergence Agitation Interventions: Drug: Propofol; Drug: Normal saline Sponsors: Khon Kaen University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 23, 2024 Category: Research Source Type: clinical trials

Recovery of TIVA vs Inhalation in Pediatric Anathesia
Conditions: Best Technique for Pediatric Anathesia Interventions: Drug: Propofol; Drug: Sevoflurane Sponsors: Assiut University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 22, 2024 Category: Research Source Type: clinical trials

Propofol-Fentanyl-Dexmedetomidine and Propofol-Fentanyl-Sevoflurane Anesthesia for Major Spine Surgery Under Somato Sensory- and Motor- Evoked Potential Monitoring
Conditions: Propofol; Fentanyl; Dexmedetomidine; Sevoflurane; Spine Surgery; Somatosensory Evoked Potential; Motor Evoked Potential Interventions: Drug: Propofol-Fentanyl; Drug: Propofol-Fentanyl-Dexmedetomidine; Drug: Propofol-Fentanyl-Sevoflurane Sponsors: Ain Shams University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 18, 2024 Category: Research Source Type: clinical trials

A Low Dose Dexmedetomidine in Sedation Colonoscopy
Conditions: Colonoscopy Interventions: Drug: Dexmedetomidine; Drug: Propofol Sponsors: West China Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials

The Anesthesia Effects of Dexmedetomidine Combined With Desflurane or Propofol in Lobectomy
Conditions: Anesthesia Recovery Period; Postoperative Complications Interventions: Drug: Dexmedetomidine and propofol; Drug: Dexmedetomidine and desflurane Sponsors: The Second Affiliated Hospital of Chongqing Medical University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials

The Efficacy of P0.1-guided Sedation Protocol in Critically Ill Patients Receiving Invasive Mechanical Ventilation: A Randomized Controlled Trial
Conditions: Respiratory Failure; Critical Illness; Respiratory Distress Syndrome, Adult; Lung Injury; Mechanical Ventilation Complication Interventions: Procedure: Titrating sedation targeting both optimal P0.1 and appropriate arousal level; Drug: Fentanyl; Drug: Midazolam; Drug: Propofol; Drug: Dexmedetomidine; Drug: Cisatracurium Sponsors: Siriraj Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 12, 2024 Category: Research Source Type: clinical trials

Comparison of the effects of esketamine, sufentanil, or lidocaine combined with propofol on tussis reflection during upper gastrointestinal endoscopy: study protocol for a randomised, two centre, three-blind, controlled trial
DiscussionEsketamine can reduce tussis occurrence with good tolerability and relax the bronchus and also provides high clearance rates and low possibility of adverse reactions. We aim to demonstrate that the combination of esketamine with propofol for sedation in patients subjected to upper GI procedure is nevertheless superior to only administration of propofol or a combination of propofol with other anaesthetics, such as opioids or lidocaine.Trial registrationClinicalTrials.gov.NCT05497492, Registered 09 August 2022. (Source: Trials)
Source: Trials - January 4, 2024 Category: Research Source Type: clinical trials

Propofol for Prophylaxis of Morphine Induced Pruritis in Caesarean Section
Conditions: Pruritus Caused by Drug Interventions: Drug: Propofol Sponsors: Assiut University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 3, 2024 Category: Research Source Type: clinical trials

The Effects of Remimazolam on the Incidence of Severe Hypoxia During Sedated Hysteroscopy for Assisted Reproduction in Overweight or Obese Patients
Conditions: Hypoxia; Hysteroscopy; Overweight or Obesity Interventions: Drug: remimazolam; Drug: Propofol Sponsors: RenJi Hospital Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 3, 2024 Category: Research Source Type: clinical trials

Dreaming during gastrointestinal endoscopy under propofol, ciprofol, or remimazolam anesthesia: study protocol for a parallel-design double-blind, single-center trial
This study may observe different incidences of dreaming and diverse types of dreams, which might lead to different evaluations to the anesthesia procedure. Based on the coming results, anesthesiologists can make a better medication plan for patients who are going to undergo painless diagnosis and treatment.Trial registrationThis trial was registered at the Chinese Clinical Trial Registry on May 18, 2023 (registration number ChiCTR2300071565). (Source: Trials)
Source: Trials - January 2, 2024 Category: Research Source Type: clinical trials

Effect of Remimazolam on Postoperative Delirium
Conditions: General Anesthetic Drug Adverse Reaction Interventions: Drug: remimazolam; Drug: propofol Sponsors: Zhihong LU Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 25, 2023 Category: Research Source Type: clinical trials