Are vasopressors effective therapy in calcium channel blocker overdose?
4 out of 5 stars Critical Care Management of Verapamil and Diltiazem Overdose with a Focus on Vasopressors: A 25-Year Experience at a Single Center. Levine M et al. Ann Emerg Med 2013 May 1 {Epub ahead of print] Abstract This uncommonly interesting and thought-provoking study comes from the Department of Medical Toxicology at Banner Good Samaritan Medical Center in Phoenix. The authors note that in recent years, many toxicologists have suggested that hyperinsulinemic euglycemic therapy (HIT) is superior to vasopressors in the treatment of calcium channel blocker (CCB) toxicity. However, there have been no studies compari...
Source: The Poison Review - May 18, 2013 Category: Toxicology Authors: Leon Tags: Best of TPR Medical calcium channel blocker toxicity diltiazem hyperinsulinemic euglycemic therapy verapamil Source Type: news

NICE unlicensed medicine evidence summary: topical diltiazem hydrochloride (2%) for chronic anal fissure
Source: NICE Area: Evidence > Drug Specific Reviews NICE unlicensed medicine evidence summary: topical diltiazem hydrochloride (2%) for chronic anal fissure   These evidence summaries review the published data for selected unlicensed or off-label medicines that are considered to be of significance to the NHS, where there are no clinically appropriate licensed alternatives. The summaries provide information for clinicians and patients to inform their decision-making and support the construction and updating of local formularies.   The latest summary addresses the use of topical diltiazem hydrochloride...
Source: NeLM - Drug Specific Reviews - January 24, 2013 Category: Drugs & Pharmacology Source Type: news