Natural bioactive compounds from medicinal plants as antibacterial drugs: mechanism insights and clinical perspectives
Curr Top Med Chem. 2022 Mar 29. doi: 10.2174/1568026622666220330011255. Online ahead of print.ABSTRACTThe coevolution in microbes has generated major functional consequences leading bacteria to develop resistance to antibiotics. Indeed, bacterial strains have been able to develop and adapt to the action of antibiotics via several resistance mechanisms. In this context, researchers are currently conducting many studies to screen natural antibacterial substances such as secondary metabolites of medicinal plants. Indeed, the potential of many plants used in traditional medicine in the treatment of infectious diseases was conf...
Source: Current Topics in Medicinal Chemistry - March 30, 2022 Category: Chemistry Authors: Nasreddine El Omari Fatima-Ezzahrae Guaouguaou Abdelhakim Bouyahya Source Type: research

Natural bioactive compounds from medicinal plants as antibacterial drugs: mechanism insights and clinical perspectives
Curr Top Med Chem. 2022 Mar 29. doi: 10.2174/1568026622666220330011255. Online ahead of print.ABSTRACTThe coevolution in microbes has generated major functional consequences leading bacteria to develop resistance to antibiotics. Indeed, bacterial strains have been able to develop and adapt to the action of antibiotics via several resistance mechanisms. In this context, researchers are currently conducting many studies to screen natural antibacterial substances such as secondary metabolites of medicinal plants. Indeed, the potential of many plants used in traditional medicine in the treatment of infectious diseases was conf...
Source: Current Topics in Medicinal Chemistry - March 30, 2022 Category: Chemistry Authors: Nasreddine El Omari Fatima-Ezzahrae Guaouguaou Abdelhakim Bouyahya Source Type: research

Natural bioactive compounds from medicinal plants as antibacterial drugs: mechanism insights and clinical perspectives
Curr Top Med Chem. 2022 Mar 29. doi: 10.2174/1568026622666220330011255. Online ahead of print.ABSTRACTThe coevolution in microbes has generated major functional consequences leading bacteria to develop resistance to antibiotics. Indeed, bacterial strains have been able to develop and adapt to the action of antibiotics via several resistance mechanisms. In this context, researchers are currently conducting many studies to screen natural antibacterial substances such as secondary metabolites of medicinal plants. Indeed, the potential of many plants used in traditional medicine in the treatment of infectious diseases was conf...
Source: Current Topics in Medicinal Chemistry - March 30, 2022 Category: Chemistry Authors: Nasreddine El Omari Fatima-Ezzahrae Guaouguaou Abdelhakim Bouyahya Source Type: research

The Effects of Commercially Available Syzygium aromaticum, Anethum graveolens, Lactobacillus acidophilus LB, and Zinc as Alternatives Therapy in Experimental Mice Challenged with Cryptosporidium parvum
(Source: Infection and Drug Resistance)
Source: Infection and Drug Resistance - January 20, 2022 Category: Infectious Diseases Tags: Infection and Drug Resistance Source Type: research

Dill Shows Potential for Herb-Drug Interactions via Up-Regulation of < em > CYP1A2 < /em > , < em > CYP2C19 < /em > , < em > SULT1A1 < /em > , < em > NAT2 < /em > and < em > ABCB1 < /em > in Caco-2 Cells
Conclusion:&lt;/b&gt; Dill extract did not directly damage Caco-2 cells but prolonged use of dill may increase the risk of HDI via the up-regulation of the drug-metabolizing genes &lt;i&gt;CYP1A2&lt;/i&gt;, &lt;i&gt;CYP2C19&lt;/i&gt;, &lt;i&gt;SULT1A1&lt;/i&gt;, &lt;i&gt;NAT2 &lt;/i&gt;and the transporter &lt;i&gt;ABCB1&lt;/i&gt;.PMID:35001576 | DOI:10.3923/pjbs.2022.56.66 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - January 10, 2022 Category: Biomedical Science Authors: Wachirawit Udomsak Waranya Chatuphonprasert Kanokwan Jarukamjorn Source Type: research

Dill Shows Potential for Herb-Drug Interactions via Up-Regulation of < em > CYP1A2 < /em > , < em > CYP2C19 < /em > , < em > SULT1A1 < /em > , < em > NAT2 < /em > and < em > ABCB1 < /em > in Caco-2 Cells
Conclusion:&lt;/b&gt; Dill extract did not directly damage Caco-2 cells but prolonged use of dill may increase the risk of HDI via the up-regulation of the drug-metabolizing genes &lt;i&gt;CYP1A2&lt;/i&gt;, &lt;i&gt;CYP2C19&lt;/i&gt;, &lt;i&gt;SULT1A1&lt;/i&gt;, &lt;i&gt;NAT2 &lt;/i&gt;and the transporter &lt;i&gt;ABCB1&lt;/i&gt;.PMID:35001576 | DOI:10.3923/pjbs.2022.56.66 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - January 10, 2022 Category: Biomedical Science Authors: Wachirawit Udomsak Waranya Chatuphonprasert Kanokwan Jarukamjorn Source Type: research

Dill Shows Potential for Herb-Drug Interactions via Up-Regulation of < em > CYP1A2 < /em > , < em > CYP2C19 < /em > , < em > SULT1A1 < /em > , < em > NAT2 < /em > and < em > ABCB1 < /em > in Caco-2 Cells
Conclusion:&lt;/b&gt; Dill extract did not directly damage Caco-2 cells but prolonged use of dill may increase the risk of HDI via the up-regulation of the drug-metabolizing genes &lt;i&gt;CYP1A2&lt;/i&gt;, &lt;i&gt;CYP2C19&lt;/i&gt;, &lt;i&gt;SULT1A1&lt;/i&gt;, &lt;i&gt;NAT2 &lt;/i&gt;and the transporter &lt;i&gt;ABCB1&lt;/i&gt;.PMID:35001576 | DOI:10.3923/pjbs.2022.56.66 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - January 10, 2022 Category: Biomedical Science Authors: Wachirawit Udomsak Waranya Chatuphonprasert Kanokwan Jarukamjorn Source Type: research

Dill Shows Potential for Herb-Drug Interactions via Up-Regulation of < em > CYP1A2 < /em > , < em > CYP2C19 < /em > , < em > SULT1A1 < /em > , < em > NAT2 < /em > and < em > ABCB1 < /em > in Caco-2 Cells
Conclusion:&lt;/b&gt; Dill extract did not directly damage Caco-2 cells but prolonged use of dill may increase the risk of HDI via the up-regulation of the drug-metabolizing genes &lt;i&gt;CYP1A2&lt;/i&gt;, &lt;i&gt;CYP2C19&lt;/i&gt;, &lt;i&gt;SULT1A1&lt;/i&gt;, &lt;i&gt;NAT2 &lt;/i&gt;and the transporter &lt;i&gt;ABCB1&lt;/i&gt;.PMID:35001576 | DOI:10.3923/pjbs.2022.56.66 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - January 10, 2022 Category: Biomedical Science Authors: Wachirawit Udomsak Waranya Chatuphonprasert Kanokwan Jarukamjorn Source Type: research

Dill Shows Potential for Herb-Drug Interactions via Up-Regulation of < em > CYP1A2 < /em > , < em > CYP2C19 < /em > , < em > SULT1A1 < /em > , < em > NAT2 < /em > and < em > ABCB1 < /em > in Caco-2 Cells
Conclusion:&lt;/b&gt; Dill extract did not directly damage Caco-2 cells but prolonged use of dill may increase the risk of HDI via the up-regulation of the drug-metabolizing genes &lt;i&gt;CYP1A2&lt;/i&gt;, &lt;i&gt;CYP2C19&lt;/i&gt;, &lt;i&gt;SULT1A1&lt;/i&gt;, &lt;i&gt;NAT2 &lt;/i&gt;and the transporter &lt;i&gt;ABCB1&lt;/i&gt;.PMID:35001576 | DOI:10.3923/pjbs.2022.56.66 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - January 10, 2022 Category: Biomedical Science Authors: Wachirawit Udomsak Waranya Chatuphonprasert Kanokwan Jarukamjorn Source Type: research

Dill Shows Potential for Herb-Drug Interactions via Up-Regulation of < em > CYP1A2 < /em > , < em > CYP2C19 < /em > , < em > SULT1A1 < /em > , < em > NAT2 < /em > and < em > ABCB1 < /em > in Caco-2 Cells
Conclusion:&lt;/b&gt; Dill extract did not directly damage Caco-2 cells but prolonged use of dill may increase the risk of HDI via the up-regulation of the drug-metabolizing genes &lt;i&gt;CYP1A2&lt;/i&gt;, &lt;i&gt;CYP2C19&lt;/i&gt;, &lt;i&gt;SULT1A1&lt;/i&gt;, &lt;i&gt;NAT2 &lt;/i&gt;and the transporter &lt;i&gt;ABCB1&lt;/i&gt;.PMID:35001576 | DOI:10.3923/pjbs.2022.56.66 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - January 10, 2022 Category: Biomedical Science Authors: Wachirawit Udomsak Waranya Chatuphonprasert Kanokwan Jarukamjorn Source Type: research

Dill Shows Potential for Herb-Drug Interactions via Up-Regulation of < em > CYP1A2 < /em > , < em > CYP2C19 < /em > , < em > SULT1A1 < /em > , < em > NAT2 < /em > and < em > ABCB1 < /em > in Caco-2 Cells
Conclusion:&lt;/b&gt; Dill extract did not directly damage Caco-2 cells but prolonged use of dill may increase the risk of HDI via the up-regulation of the drug-metabolizing genes &lt;i&gt;CYP1A2&lt;/i&gt;, &lt;i&gt;CYP2C19&lt;/i&gt;, &lt;i&gt;SULT1A1&lt;/i&gt;, &lt;i&gt;NAT2 &lt;/i&gt;and the transporter &lt;i&gt;ABCB1&lt;/i&gt;.PMID:35001576 | DOI:10.3923/pjbs.2022.56.66 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - January 10, 2022 Category: Biomedical Science Authors: Wachirawit Udomsak Waranya Chatuphonprasert Kanokwan Jarukamjorn Source Type: research

Dill Shows Potential for Herb-Drug Interactions via Up-Regulation of < em > CYP1A2 < /em > , < em > CYP2C19 < /em > , < em > SULT1A1 < /em > , < em > NAT2 < /em > and < em > ABCB1 < /em > in Caco-2 Cells
Conclusion:&lt;/b&gt; Dill extract did not directly damage Caco-2 cells but prolonged use of dill may increase the risk of HDI via the up-regulation of the drug-metabolizing genes &lt;i&gt;CYP1A2&lt;/i&gt;, &lt;i&gt;CYP2C19&lt;/i&gt;, &lt;i&gt;SULT1A1&lt;/i&gt;, &lt;i&gt;NAT2 &lt;/i&gt;and the transporter &lt;i&gt;ABCB1&lt;/i&gt;.PMID:35001576 | DOI:10.3923/pjbs.2022.56.66 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - January 10, 2022 Category: Biomedical Science Authors: Wachirawit Udomsak Waranya Chatuphonprasert Kanokwan Jarukamjorn Source Type: research

Dill Shows Potential for Herb-Drug Interactions via Up-Regulation of < em > CYP1A2 < /em > , < em > CYP2C19 < /em > , < em > SULT1A1 < /em > , < em > NAT2 < /em > and < em > ABCB1 < /em > in Caco-2 Cells
Conclusion:&lt;/b&gt; Dill extract did not directly damage Caco-2 cells but prolonged use of dill may increase the risk of HDI via the up-regulation of the drug-metabolizing genes &lt;i&gt;CYP1A2&lt;/i&gt;, &lt;i&gt;CYP2C19&lt;/i&gt;, &lt;i&gt;SULT1A1&lt;/i&gt;, &lt;i&gt;NAT2 &lt;/i&gt;and the transporter &lt;i&gt;ABCB1&lt;/i&gt;.PMID:35001576 | DOI:10.3923/pjbs.2022.56.66 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - January 10, 2022 Category: Biomedical Science Authors: Wachirawit Udomsak Waranya Chatuphonprasert Kanokwan Jarukamjorn Source Type: research

Dill Shows Potential for Herb-Drug Interactions via Up-Regulation of < em > CYP1A2 < /em > , < em > CYP2C19 < /em > , < em > SULT1A1 < /em > , < em > NAT2 < /em > and < em > ABCB1 < /em > in Caco-2 Cells
Conclusion:&lt;/b&gt; Dill extract did not directly damage Caco-2 cells but prolonged use of dill may increase the risk of HDI via the up-regulation of the drug-metabolizing genes &lt;i&gt;CYP1A2&lt;/i&gt;, &lt;i&gt;CYP2C19&lt;/i&gt;, &lt;i&gt;SULT1A1&lt;/i&gt;, &lt;i&gt;NAT2 &lt;/i&gt;and the transporter &lt;i&gt;ABCB1&lt;/i&gt;.PMID:35001576 | DOI:10.3923/pjbs.2022.56.66 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - January 10, 2022 Category: Biomedical Science Authors: Wachirawit Udomsak Waranya Chatuphonprasert Kanokwan Jarukamjorn Source Type: research

Dill Shows Potential for Herb-Drug Interactions via Up-Regulation of < em > CYP1A2 < /em > , < em > CYP2C19 < /em > , < em > SULT1A1 < /em > , < em > NAT2 < /em > and < em > ABCB1 < /em > in Caco-2 Cells
Conclusion:&lt;/b&gt; Dill extract did not directly damage Caco-2 cells but prolonged use of dill may increase the risk of HDI via the up-regulation of the drug-metabolizing genes &lt;i&gt;CYP1A2&lt;/i&gt;, &lt;i&gt;CYP2C19&lt;/i&gt;, &lt;i&gt;SULT1A1&lt;/i&gt;, &lt;i&gt;NAT2 &lt;/i&gt;and the transporter &lt;i&gt;ABCB1&lt;/i&gt;.PMID:35001576 | DOI:10.3923/pjbs.2022.56.66 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - January 10, 2022 Category: Biomedical Science Authors: Wachirawit Udomsak Waranya Chatuphonprasert Kanokwan Jarukamjorn Source Type: research