PPAR gamma agonistic activity of dillapiole: protective effects against diabetic nephropathy
Nat Prod Res. 2024 Apr 2:1-6. doi: 10.1080/14786419.2024.2334323. Online ahead of print.ABSTRACTUsing structural similarity approach we identified dillapiole, a phenylpropanoid, the main component of Piper aduncum L. and Anethum graveolens L. essential oils as potential PPARγ agonist. Molecular docking revealed that dillapiole binds to the active site of PPARγ, similar to pioglitazone binding. In silico ADME studies showed that dillapiole has high water solubility and GI absorption. Dillapiole was also observed to be partial agonist of PPARγ receptors with EC50 of 43.95 µM. In BHK-21 cells cultured under hyperglycaemic...
Source: Natural Product Research - April 2, 2024 Category: Biochemistry Authors: Sana Shafi Navneet Khurana Jeena Gupta Source Type: research
Effect of Dill ( < em > Anethum graveolens < /em > ) Oil on Pruritus and Quality of Life of Hemodialysis Patients: A Randomized Double-Blind Three-Arm Controlled Trial
CONCLUSION: Topical Anethum graveolens preparation significantly improved the sleep quality and quality of life and reduced skin pruritus and dryness in hemodialysis patients. It could be considered as a simple therapeutic modality to control pruritus in hemodialysis patients. This trial is registered with IRCT2017022032671N1.PMID:38264189 | PMC:PMC10805558 | DOI:10.1155/2024/3077603 (Source: Evidence-based Complementary and Alternative Medicine)
Source: Evidence-based Complementary and Alternative Medicine - January 24, 2024 Category: Complementary Medicine Authors: Zeinab Shaki Farzaneh Ghaffari Fatemeh Alijaniha Mohammad Kamalinejad Anoshiravan Kazemnejad Babak Daneshfard Mohsen Naseri Mohammad Reza Heidari Source Type: research
Catalytic Application of Green-Synthesized ZnO Nanoparticles in the Synthesis of 1H-pyrazolo[1,2-a]pyridazine-5,8-diones and Evaluation of Their Anti-Cancer Properties †
In this study, Zinc Oxide Nanoparticles (ZnO NPs) produced utilizing Dill (Anethum graveolens) leaf extract and as a very efficient nanocatalyst, have been used for the green preparation of 1H-pyrazolo[1,2-a]pyridazine-5,8-diones... The content of this RSS Feed (c) The Royal Society of Chemistry (Source: RSC - New J. Chem. latest articles)
Source: RSC - New J. Chem. latest articles - July 27, 2023 Category: Chemistry Authors: Soma Majedi Source Type: research
Induction role of chitosan nanoparticles to Anethum graveolens extract against food-borne bacteria, oxidant, and diabetic activities in vitro
Foodborne diseases as well as Foodborne pathogens are a global issue with significant effects on human health and economy. Therefore, several investigators have tried to find new alternative approaches to prevent and control this problem. In this context, the present study aimed to find some possible and effective approaches for controlling food-borne bacteria via Dill (Anethum graveolens L.) extract (DE) loaded with chitosan nanoparticles (ChNPs) besides its anti-oxidant and anti-diabetic activities. Flavonoid and phenolic contents of DE were detected by HPLC, indicating the presence of 18 constituents, high content (2252...
Source: Frontiers in Microbiology - July 4, 2023 Category: Microbiology Source Type: research
Biodegradable antifungal films from nanocellulose-gellan gum incorporated with Anethum graveolens essential oil for bread packaging
Int J Biol Macromol. 2023 Jun 7;243:125244. doi: 10.1016/j.ijbiomac.2023.125244. Online ahead of print.ABSTRACTBiodegradable material incorporated with antifungal essential oil has become an alternative food preservation approach to reduce plastic waste. Essential oils of Amomum testaceum, Anethum graveolens, Piper longum, Kaempferia galanga, and Zanthoxylum limonella were tested for their antifungal activity against Aspergillus niger. A. graveolens essential oil demonstrated the highest inhibition zone diameter of 43.51 mm against A. niger after seven days comparing to those obtained from other essential oils ranging from...
Source: International Journal of Biological Macromolecules - June 8, 2023 Category: Biochemistry Authors: Teerapong Sripahco Sarunpron Khruengsai Patcharee Pripdeevech Source Type: research
Biodegradable antifungal films from nanocellulose-gellan gum incorporated with Anethum graveolens essential oil for bread packaging
Int J Biol Macromol. 2023 Jun 6:125244. doi: 10.1016/j.ijbiomac.2023.125244. Online ahead of print.ABSTRACTBiodegradable material incorporated with antifungal essential oil has become an alternative food preservation approach to reduce plastic waste. Essential oils of Amomum testaceum, Anethum graveolens, Piper longum, Kaempferia galanga, and Zanthoxylum limonella were tested for their antifungal activity against Aspergillus niger. A. graveolens essential oil demonstrated the highest inhibition zone diameter of 43.51 mm against A. niger after seven days comparing to those obtained from other essential oils ranging from 10....
Source: International Journal of Biological Macromolecules - June 8, 2023 Category: Biochemistry Authors: Teerapong Sripahco Sarunpron Khruengsai Patcharee Pripdeevech Source Type: research
Amalgamation of quercetin with anastrozole and capecitabine: A novel combination to treat breast and colon cancers - An < em > in vitro < /em > study
CONCLUSIONS: The natural compound used in the present study is effective in treating breast and colon cancer at minimal concentrations in combination with the drugs. This combinational treatment appears to be reported for the first time in the present study.PMID:37147989 | DOI:10.4103/jcrt.JCRT_599_20 (Source: Cell Research)
Source: Cell Research - May 6, 2023 Category: Cytology Authors: Mary Shobha Rani Inala Kiranmayee Pamidimukkala Source Type: research
Amalgamation of quercetin with anastrozole and capecitabine: A novel combination to treat breast and colon cancers - An < em > in vitro < /em > study
CONCLUSIONS: The natural compound used in the present study is effective in treating breast and colon cancer at minimal concentrations in combination with the drugs. This combinational treatment appears to be reported for the first time in the present study.PMID:37147989 | DOI:10.4103/jcrt.JCRT_599_20 (Source: Cancer Control)
Source: Cancer Control - May 6, 2023 Category: Cancer & Oncology Authors: Mary Shobha Rani Inala Kiranmayee Pamidimukkala Source Type: research
Cinnamomum verum J. Presl. Bark essential oil: in vitro investigation of anti-cholinesterase, anti-BACE1, and neuroprotective activity
Cinnamomum verum J. Presl. (Lauraceae), Myrtus communis L. (Myrtaceae), Ruta graveolens L. (Rutaaceae), Anethum graveolens L. (Apiaceae), Myristica fragrans Houtt. (Myristicaceae), and Crocus sativus L. (Iridacea... (Source: BMC Complementary and Alternative Medicine)
Source: BMC Complementary and Alternative Medicine - November 18, 2022 Category: Complementary Medicine Authors: Mina Saeedi, Aida Iraji, Yasaman Vahedi-Mazdabadi, Atiyeh Alizadeh, Najmeh Edraki, Omidreza Firuzi, Mahdieh Eftekhari and Tahmineh Akbarzadeh Tags: Research Source Type: research
Biochar-based nutritional nanocomposites: a superior treatment for alleviating salt toxicity and improving physiological performance of dill (Anethum graveolens)
AbstractBiochar-supported metal oxide nanocomposites as functional materials could help to improve the production and stress tolerance of plants by enhancing the physicochemical properties of biochar. This experiment was carried out to assess the effects of unmodified biochar (30 g kg−1 soil) and biochar-based nanocomposites (BNCs) of iron (30 g BNC-FeO kg−1 soil), zinc (30 g BNC-ZnO kg−1 soil), and a combined form (15 g BNC-FeO + 15 g BNC-ZnO kg−1 soil) on dill (Anethum graveolens L.) plants under various salinity levels (non-saline, 6 and 12 dS m−1). The biochar-related treatments reduced sod...
Source: Environmental Geochemistry and Health - September 25, 2022 Category: Environmental Health Source Type: research
The effects of Anethum graveolens (dill) supplementation on lipid profile and glycemic control: a systematic review and meta-analysis of randomized controlled trials
(Source: Critical Reviews in Food Science and Nutrition)
Source: Critical Reviews in Food Science and Nutrition - July 21, 2022 Category: Nutrition Authors: Mousavi, Seyed Mohammad Beatriz Pizarro, Ana Akhgarjand, Camellia Bagheri, Amir Persad, Emma Karimi, Elmira Wong, Alexei Jayedi, Ahmad Source Type: research
Native Iranian Medicinal Plants with Anti-Vaginal Infection Properties: A Systematic Review
CONCLUSION: Therefore, native plants of Iran have been reported to have antimicrobial properties for the treatment of vaginal infections and can be used as a suitable and effective alternative to antibiotics in future research.PMID:35490427 | DOI:10.2174/1871526522666220501171551 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - May 1, 2022 Category: Infectious Diseases Authors: Marzieh Rashidipour Pegah Shakib Gholamreza Goudarzi Yadollah Pournia Maryam Karimi Maryam Sarlak Source Type: research
Native Iranian Medicinal Plants with Anti-Vaginal Infection Properties: A Systematic Review
CONCLUSION: Therefore, native plants of Iran have been reported to have antimicrobial properties for the treatment of vaginal infections and can be used as a suitable and effective alternative to antibiotics in future research.PMID:35490427 | DOI:10.2174/1871526522666220501171551 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - May 1, 2022 Category: Infectious Diseases Authors: Marzieh Rashidipour Pegah Shakib Gholamreza Goudarzi Yadollah Pournia Maryam Karimi Maryam Sarlak Source Type: research
Native Iranian Medicinal Plants with Anti-Vaginal Infection Properties: A Systematic Review
CONCLUSION: Therefore, native plants of Iran have been reported to have antimicrobial properties for the treatment of vaginal infections and can be used as a suitable and effective alternative to antibiotics in future research.PMID:35490427 | DOI:10.2174/1871526522666220501171551 (Source: Infectious Disorders Drug Targets)
Source: Infectious Disorders Drug Targets - May 1, 2022 Category: Infectious Diseases Authors: Marzieh Rashidipour Pegah Shakib Gholamreza Goudarzi Yadollah Pournia Maryam Karimi Maryam Sarlak Source Type: research
Natural bioactive compounds from medicinal plants as antibacterial drugs: mechanism insights and clinical perspectives
Curr Top Med Chem. 2022 Mar 29. doi: 10.2174/1568026622666220330011255. Online ahead of print.ABSTRACTThe coevolution in microbes has generated major functional consequences leading bacteria to develop resistance to antibiotics. Indeed, bacterial strains have been able to develop and adapt to the action of antibiotics via several resistance mechanisms. In this context, researchers are currently conducting many studies to screen natural antibacterial substances such as secondary metabolites of medicinal plants. Indeed, the potential of many plants used in traditional medicine in the treatment of infectious diseases was conf...
Source: Current Topics in Medicinal Chemistry - March 30, 2022 Category: Chemistry Authors: Nasreddine El Omari Fatima-Ezzahrae Guaouguaou Abdelhakim Bouyahya Source Type: research
