Painkiller increases chance of heart attack, health officials advise
Experts says patients with heart conditions should stop using diclofenac after study finds stroke and heart attack linkHealth officials have advised patients with heart problems to avoid an over-the-counter painkiller used by millions after research found that it can significantly increase the risk of heart attack or stroke.The Medicines and Healthcare products Regulatory Agency (MHRA) said that patients with an underlying heart condition, such as heart failure, heart disease or circulatory problems, or patients who have previously suffered heart attacks or strokes, should no longer use diclofenac.An MHRA spokesman said th...
Source: Guardian Unlimited Science - June 29, 2013 Category: Science Tags: Heart attack The Guardian News Health Society Drugs UK news Science Source Type: news

Diclofenac Poses Similar Risks as COX-2 InhibitorsDiclofenac Poses Similar Risks as COX-2 Inhibitors
The committee says the benefits of diclofenac exceed the known risks and that physicians should take the same precautions to minimize thromboembolic risk as they do with patients treated with selective COX-2 inhibitors. Heartwire (Source: Medscape Today Headlines)
Source: Medscape Today Headlines - June 14, 2013 Category: Consumer Health News Tags: Cardiology News Source Type: news

EMA committee concludes diclofenac poses similar risks as COX-2 inhibitors
The committee says the benefits of diclofenac exceed the known risks and that physicians should take the same precautions to minimize thromboembolic risk as they do with patients treated with selective COX-2 inhibitors. (Source: theHeart.org)
Source: theHeart.org - June 14, 2013 Category: Cardiology Source Type: news

EU regulator advises caution on painkiller diclofenac
LONDON (Reuters) - Europe's drugs agency warned on Friday that use of the common painkiller diclofenac, especially in high doses, carries extra heart attack risks which should be taken into consideration by doctors prescribing the drug. (Source: Reuters: Health)
Source: Reuters: Health - June 14, 2013 Category: Consumer Health News Tags: healthNews Source Type: news

No Added Benefit Of Ingenol Mebutate For Actinic Keratosis
Manufacturer's dossier did not contain any relevant data for the comparison with diclofenac/hyaluronic acid gel The drug ingenol mebutate (trade name: Picato) has been approved in Germany since November 2012 as a gel for the treatment of certain forms of actinic keratosis in adults. In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG) the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether this new drug offers an added benefit over diclofenac/hyaluronic acid gel... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - June 10, 2013 Category: Consumer Health News Tags: Dermatology Source Type: news

Rwanda: Ministry Downplays Warning On Painkillers
[New Times]Diclofenac and ibuprofen, two painkillers British researchers have concluded can increase the risk of heart diseases, should not cause alarm as the benefits on proper dispensation outweighs the "long-term" risks, health officials have said. (Source: AllAfrica News: Health and Medicine)
Source: AllAfrica News: Health and Medicine - June 7, 2013 Category: African Health Source Type: news

Anti-inflammatory medications ibuprofen, diclofenac may up heart issues
High doses of ibuprofen and diclofenac taken over a year lead to an one-third increase of heart attack, stroke or early death risk (Source: Health News: CBSNews.com)
Source: Health News: CBSNews.com - May 30, 2013 Category: Consumer Health News Source Type: news

Painkillers Linked To Higher Risk Of Heart Attack
High doses of some of the most common painkillers, including ibuprofen and diclofenac, can increase the risk of heart problems by nearly thirty percent, according to a new study published in The Lancet. The researchers conducted a meta-analysis of clinical trials to analyze the risks associated with taking nonsteroidal anti-inflammatory drugs (NSAIDs) -including selective COX-2 inhibitors (coxibs) and traditional non-steroidal anti-inflammatory drugs (tNSAIDs). NSAIDs are medications with analgesic (pain reducing) and antipyretic (fever reducing) properties... (Source: Health News from Medical News Today)
Source: Health News from Medical News Today - May 30, 2013 Category: Consumer Health News Tags: Pain / Anesthetics Source Type: news

High-dose painkiller heart risk: small but significant
Conclusion This large review adds to, and expands on, the current evidence on the risks of vascular disease and gastrointestinal complications for different NSAIDs. It largely concentrates on trials of high doses of NSAIDs that can only be prescribed by a doctor. It is unclear from this study whether there is any risk from taking lower doses available over the counter. While most experts advise that low-dose NSAIDs, taken occasionally, are safe for most people, an accompanying editorial points out that there are still “large gaps” in evidence on the risks with lower doses of NSAIDs. While the risk to individuals is sma...
Source: NHS News Feed - May 30, 2013 Category: Consumer Health News Tags: Medication Heart/lungs Source Type: news

Painkillers can increase risk of heart attack, study says
Drugs used for conditions such as arthritis pose slight risk if taken in high doses over a long time, research findsHigh doses of painkillers such as diclofenac and ibuprofen have been found to increase the chance of heart problems by a small amount, according to research.Carried out by the MRC Clinical Trial Service Unit and Epidemiological Studies Unit at the University of Oxford and published in the Lancet, the research is based on data from outcomes of more than 353,000 patients and focuses on prolonged use of non-steroidal anti-inflammatory drugs in high doses. Nsaids are widely used by people suffering from condition...
Source: Guardian Unlimited Science - May 30, 2013 Category: Science Authors: Press Association Tags: Medical research Drugs Health Society Science Heart attack UK news World news Source Type: news

Painkillers can increase risk of heart attack, study says
Drugs used for conditions such as arthritis pose slight risk if taken in high doses over a long time, research findsHigh doses of painkillers such as diclofenac and ibuprofen have been found to increase the chance of heart problems by a small amount, according to research.Carried out by the MRC Clinical Trial Service Unit and Epidemiological Studies Unit at the University of Oxford and published in the Lancet, the research is based on data from outcomes of more than 353,000 patients and focuses on prolonged use of non-steroidal anti-inflammatory drugs in high doses. Nsaids are widely used by people suffering from condition...
Source: Guardian Unlimited Science - May 30, 2013 Category: Science Tags: Heart attack News Health guardian.co.uk Society Drugs Science Source Type: news

Painkillers taken by millions could increase heart risk: Prolonged use 'leads to significant danger'
The drugs, known as non-steroidal anti-inflammatory drugs (NSAIDs), include ibuprofen and diclofenac, and also newer medication called coxibs. (Source: the Mail online | Health)
Source: the Mail online | Health - May 30, 2013 Category: Consumer Health News Source Type: news

VIDEO: Common painkillers 'pose heart risk'
Two common painkillers, ibuprofen and diclofenac, can slightly increase the risk of heart problems if taken in high doses for a long time, data suggests. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - May 30, 2013 Category: Consumer Health News Source Type: news

Common painkillers 'pose heart risk'
Some common painkillers, including ibuprofen and diclofenac, may slightly increase the risk of heart problems if taken in high doses for a long time, data suggests. (Source: BBC News | Health | UK Edition)
Source: BBC News | Health | UK Edition - May 29, 2013 Category: Consumer Health News Source Type: news

High doses of common painkillers increase heart attack risks
LONDON (Reuters) - Long-term high-dose use of painkillers such as ibuprofen or diclofenac is "equally hazardous" in terms of heart attack risk as use of the drug Vioxx, which was withdrawn due to its potential dangers, researchers said on Thursday. (Source: Reuters: Health)
Source: Reuters: Health - May 29, 2013 Category: Consumer Health News Tags: healthNews Source Type: news