Intravenous Immunoglobulin Replacement Therapy for Persistent COVID-19 in Patients With B-cell Impairment
Conditions: COVID-19 Interventions: Drug: Immunoglobulins Sponsors: Jaehoon Ko Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 6, 2023 Category: Research Source Type: clinical trials
Quality of Life After Hyperbaric Oxygen Therapy in Post-COVID Patients
Conditions: Long COVID; Long COVID-19 Syndrome; Long Covid19; Long Covid 19 Interventions: Other: Hyperbaric oxygen therapy Sponsors: Rutger Lalieu; DaVinci Kliniek Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 6, 2023 Category: Research Source Type: clinical trials
Effect of Inhaled Hydroxy Gas on Long COVID Symptoms
Conditions: Post-Acute COVID-19 Syndrome Interventions: Device: Hydroxy gas Sponsors: Oxford Brookes University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 6, 2023 Category: Research Source Type: clinical trials
COVID-19 Personal Protective Equipment for Vaccinated Health Workers and Convalescents
Conditions: Covid19 Interventions: Other: Personal Protective Equipment Sponsors: University Medical Centre Ljubljana Withdrawn (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 6, 2023 Category: Research Source Type: clinical trials
Challenges of conducting a randomised placebo-controlled trial of spinal surgery: the SUcceSS trial of lumbar spine decompression
AbstractAlthough placebo-controlled trials are considered the gold standard for evaluating the efficacy of healthcare interventions, they can be perceived to be controversial and challenging to conduct for surgical treatments. The SUcceSS trial is the first placebo-controlled trial of lumbar decompression surgery for symptomatic lumbar canal stenosis. The SUcceSS trial has experienced common issues affecting the implementation of randomised placebo-controlled surgery trials, accentuated by the COVID-19 pandemic. Using the SUcceSS trial as an example, we discuss key challenges and mitigation strategies specific to the condu...
Source: Trials - December 6, 2023 Category: Research Source Type: clinical trials
Community Care Intervention to Decrease COVID-19 Vaccination Inequities
Conditions: COVID-19 Vaccination Interventions: Behavioral: Community Health Worker Intervention to Enhance Vaccination Behavior (CHW-VB) Sponsors: RAND; Clinical Directors Network; National Institute on Minority Health and Health Disparities (NIMHD) Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 5, 2023 Category: Research Source Type: clinical trials
PROmotion of COVID-19 BOOSTer VA(X)Ccination in the Emergency Department - PROBOOSTVAXED
Conditions: COVID-19 Interventions: Behavioral: Vaccine Messaging; Behavioral: Vaccine Acceptance Question Sponsors: University of California, San Francisco; National Institute of Allergy and Infectious Diseases (NIAID); Pfizer; Duke University; Baylor College of Medicine; Thomas Jefferson University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 5, 2023 Category: Research Source Type: clinical trials
Multilevel Intervention of COVID-19 Vaccine Uptake Among Latinos
Conditions: Vaccine Hesitancy Interventions: Behavioral: Multilevel Intervention Sponsors: San Diego State University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 5, 2023 Category: Research Source Type: clinical trials
Evaluating a Comprehensive Multimodal Outpatient Rehabilitation Program for PASC Program to Improve Functioning of Persons Suffering From Post-COVID Syndrome: A Randomized Controlled Trial
Conditions: Post-Acute COVID-19; Post-Acute COVID-19 Syndrome; Post-Acute COVID-19 Infection; Long COVID; Long Covid19; Dyspnea; Orthostasis; Cognitive Impairment Interventions: Other: Comprehensive Rehabilitation; Other: Augmented Usual Care Sponsors: University of Pennsylvania; Medical College of Wisconsin; National Institutes of Health (NIH) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 5, 2023 Category: Research Source Type: clinical trials
Stem Cell Study for Long COVID-19 Neurological Symptoms
Conditions: Post-Acute COVID-19 Syndrome Interventions: Biological: Stem Cell Sponsors: Charles Cox; CBR Systems, Inc. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 5, 2023 Category: Research Source Type: clinical trials
Pursuing Reduction in Fatigue After COVID-19 Via Exercise and Rehabilitation (PREFACER): A Randomized Feasibility Trial
Conditions: Long-COVID; Long Covid19; Post-COVID-19 Syndrome; Post-COVID Syndrome; Fatigue Interventions: Other: COVIDEx Sponsors: Lawson Health Research Institute; Western University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 5, 2023 Category: Research Source Type: clinical trials
Characteristics of Blood Glucose Variability in Patients With Type 2 Diabetes Mellitus and COVID-19
Conditions: COVID-19 Pneumonia; Type2diabetes Interventions: Other: Glucose variability Sponsors: Qilu Hospital of Shandong University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 5, 2023 Category: Research Source Type: clinical trials
An Observational Study to Describe EVUSHELD ™ (Tixagevimab/Cilgavimab) Pre-exposure Prophylaxis in Real-world Setting in Japan
Conditions: COVID-19 Interventions: Drug: Evusheld Sponsors: AstraZeneca Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - December 5, 2023 Category: Research Source Type: clinical trials
Characterization of COVID-19 vaccine clinical trial discussions on the social question-and-answer site Quora
ConclusionsOur study found active user discussions related to COVID-19 vaccine clinical trials on Quora, including those specific to minority health topics and those posted by a smaller group of self-identified racial and ethnic minority online users. Results from this study can help identify barriers to participation among the general public and underrepresented groups while also supporting the design of future outreach strategies to help with recruitment and inclusive trial participation. (Source: Trials)
Source: Trials - December 5, 2023 Category: Research Source Type: clinical trials
A randomized double-blind clinical trial on safety and efficacy of tauroursodeoxycholic acid (TUDCA) as add-on treatment in patients affected by amyotrophic lateral sclerosis (ALS): the statistical analysis plan of TUDCA-ALS trial
DiscussionThis paper provides a comprehensive description of the statistical analysis plan in order to ensure the reproducibility of the analysis and avoid selective reporting of outcomes and data-driven analysis. Sensitivity analyses have been included in the protocol to assess the impact of intercurrent events related to the coronavirus disease 2019. By focusing on clinically meaningful and robust outcomes, this trial aims to determine whether TUDCA can be effective in slowing the disease progression in patients with ALS.Trial registrationClinicalTrials.govNCT03800524. Registered on January 11, 2019. (Source: Trials)
Source: Trials - December 5, 2023 Category: Research Source Type: clinical trials
