Mitoxantrone Hydrochloride Liposome Injection-containing Bridging Regimen and CD19-targeting CAR-T Therapies
Conditions: B-cell Acute Lymphoblastic Leukemia; B-cell Lymphoma Refractory Interventions: Drug: Mitoxantrone hydrochloride liposome Injection-based bridging therapy+ Fludarabine-based chemotherapy +CD19 CAR-T Cells Sponsors: Wuhan Union Hospital, China; CSPC Pharmaceutical Group Limited Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 23, 2024 Category: Research Source Type: clinical trials
Working under short timescales to deliver a national trial: a case study of the ComFluCOV trial from a statistician ’s perspective
ConclusionThe statistical methodologies implemented in ComFluCOV helped to deliver the study in the timescale set. Working in a new clinical area to tight timescales was challenging. Having two statisticians working together on the study provided a quality assurance process that enabled analyses to be completed efficiently and ensured data were interpreted correctly. Processes developed could be applied to other studies to maximise quality, reduce the risk of errors, and overall provide enhanced validation methods.Trial registrationISRCTN14391248, registered on 30 March 2021 (Source: Trials)
Source: Trials - January 23, 2024 Category: Research Source Type: clinical trials
Beneficial Effects of Natural Products on Management of Xerostomia
Conditions: Xerostomia; Diabetes Mellitus; Hypertension; Post COVID-19 Condition Interventions: Other: (Manuka honey-green tea- ginger) Sponsors: British University In Egypt Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 22, 2024 Category: Research Source Type: clinical trials
Efficacy and safety of azvudine in symptomatic adult COVID-19 participants who are at increased risk of progressing to critical illness: a study protocol for a multicentre randomized double-blind placebo-controlled phase III trial
DiscussionThe purpose of this clinical trial is to determine whether azvudine can prevent patients at risk of severe disease from progressing to critical illness and death, and the results will identify whether azvudine is an effective and affordable antiviral treatment option for COVID-19.Trial registrationClinicalTrials.gov NCT05689034. Registered on 18 January 2023. (Source: Trials)
Source: Trials - January 22, 2024 Category: Research Source Type: clinical trials
Diet and Fasting for Long COVID
Conditions: Long Covid19; Long COVID Interventions: Other: Low sugar diet and 10-12 hour eating window; Other: Low sugar diet, 8 hour eating window and fasting Sponsors: Pacific Northwest University of Health Sciences Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 19, 2024 Category: Research Source Type: clinical trials
Admission Pattern Among Children With Gastro-intestinal Infections Before and During the Covid-19 Pandemic
Conditions: Gastroenteritis; Rota Virus Gastroenteritis; Dehydration in Children; Infectious Disease; COVID-19 Pandemic; Norovirus Infections Sponsors: Region Zealand Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 18, 2024 Category: Research Source Type: clinical trials
The Effectiveness of a Health Promotion Program for Older People With Post-Covid-19 Sarcopenia
Conditions: Post COVID-19 Condition Interventions: Other: Protein powder and Resistance exercise Sponsors: Mahidol University; National Health Security Office, Thailand Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 18, 2024 Category: Research Source Type: clinical trials
Wearable Assisted Viral Evidence (WAVE) Study A Decentralized, Prospective Study Exploring the Relationship Between Passively-collected Data From Wearable Activity Devices and Respiratory Viral Infections
Conditions: Influenza, Human; COVID-19; Influenza A; Influenza B; Respiratory Syncytial Virus (RSV) Sponsors: Evidation Health; Biomedical Advanced Research and Development Authority Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
Neural and Cognitive Consequences of COVID-19 Survival
Conditions: COVID Long-Haul; COVID-19; COVID-19 Pandemic; Brain Fog; Memory Deficits; Concentration Ability Impaired; Fatigue Interventions: Other: cross-sectional MRI and EEG assessments (NO INTERVENTION) Sponsors: San Francisco Veterans Affairs Medical Center Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
Prevalence and Risk Indicators of Peri-implant Diseases in China
Conditions: Peri-Implantitis Sponsors: Shanghai Ninth People ' s Hospital Affiliated to Shanghai Jiao Tong University; Dalian Medical University; Nanchang University; Ningxia Medical University; Shanxi Medical University; Hospital of Stomatology, Wuhan University; Hospital of Stomatology, Sun Yat-Sen University; Zunyi Medical College; Hong Kong Br ånemark Osseointegration Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
Treatment of Persistent Post-Covid-19 Smell and Taste Disorders
Conditions: Post-covid-19 Persistent Smell and Taste Disorders Interventions: Drug: Cerebrolysin; Other: olfactory and gustatory trainings Sponsors: Sherifa Ahmed Hamed Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
Chronic-disease Self-management Program in Patients Living With Long-COVID in Puerto Rico
Conditions: Long Covid19 Interventions: Other: " Tomando control de su salud " (Spanish Chronic Disease Self-Management) Sponsors: University of Puerto Rico; National Institutes of Health (NIH) Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
Traditional Chinese Acupoint Massage for Gastrointestinal Function Recovery
Conditions: Traditional Chinese Acupoint Message; Intestinal Barrier; Gastrointestinal Dysfunction Sponsors: Wuhan Union Hospital, China Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
Comparative Study of AnaConDa System Use Versus Conventional Sedation in COVID-19 Patients.
Conditions: SARS CoV 2 Infection; Mechanical Ventilation Complication Interventions: Device: USE OF SEVOFLURANE WITH AnaConDa Sponsors: Hospital Espa ñol de Mexico; Universidad Nacional Autonoma de Mexico Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 17, 2024 Category: Research Source Type: clinical trials
A Study to Evealuate Safety and Immunogenicity of TI-0010 SARS-CoV-2 Vaccine in Healthy Adults
Conditions: COVID-19; COVID-19 Immunisation Interventions: Biological: TI-0010; Biological: Placebo Sponsors: National Drug Clinical Trial Institute of the Second Affiliated Hospital of Bengbu Medical College; Therorna Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - January 16, 2024 Category: Research Source Type: clinical trials
