A randomised controlled trial assessing the use of citalopram, sertraline, fluoxetine and mirtazapine in preventing relapse in primary care patients who are taking long-term maintenance antidepressants (ANTLER: ANTidepressants to prevent reLapse in dEpRession): study protocol for a randomised controlled trial
This article describes the protocol for a randomised controlled trial (ANTLER: ANTidepressants to prevent reLapse in dEpRession) to investigate the clinical effectiveness and cost-effectiveness in UK primary care of continuing on long-term maintenance antidepressants compared with a placebo in preventing relapse of depression in those who have taken antidepressants for more than 9 months and who are currently well enough to consider stopping maintenance treatment.Methods/designThe ANTLER trial is an individually randomised, double-blind, placebo-controlled trial in which participants are randomised to remain on active m...
Source: Trials - June 2, 2019 Category: Research Source Type: clinical trials
A Clinical Study to Examine the Drug-drug Interactions Between ACT-541468 and Citalopram in Healthy Male and Female Subjects
Condition: Healthy Interventions: Drug: ACT541468; Drug: ACT541468 placebo; Drug: Citalopram Sponsor: Idorsia Pharmaceuticals Ltd. Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 8, 2019 Category: Research Source Type: clinical trials
A Clinical Study to Examine the Drug-drug Interactions Between ACT-541468 and Citalopram in Healthy Male and Female Subjects
Condition: Healthy Interventions: Drug: ACT541468; Drug: ACT541468 placebo; Drug: Citalopram Sponsor: Idorsia Pharmaceuticals Ltd. Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 8, 2019 Category: Research Source Type: clinical trials
