Protocol for a randomized control trial of the Building Regulation in Dual Generations Program (BRIDGE): preventing the intergenerational transmission of mental illness in at-risk preschool children
DiscussionDual-generation programs offer an innovative approach to prevent the intergenerational transmission of mental illness. The current study will add to the evidence base for BRIDGE by comparing it to a stand-alone mental health intervention and a services-as-usual group. These comparisons will provide valuable information on the relative efficacy of including parenting support in a mental health intervention for parents. The results will contribute to our understanding of how maternal depression affects children ’s development and how intervening at both a mental health and parenting level may affect child and fam...
Source: Trials - September 19, 2023 Category: Research Source Type: clinical trials

Guanfacine for Hyperactivity in Children With Down Syndrome (HYPEbeGONE_DS)
Conditions:   Hyperactivity in Children With Down Syndrome;   Impulsivity in Children With Down Syndrome Interventions:   Drug: Guanfacine Hydrochloride Immediate Release;   Drug: Placebo Sponsors:   Rachel G. Greenberg, MD, MB, MHS;   The Emmes Company, LLC;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 18, 2023 Category: Research Source Type: clinical trials

Sensory Processing Skills in Toddler With Joint Hypermobility
Conditions:   Child Development;   Sensory Disorder;   Hypermobility, Joint Intervention:   Diagnostic Test: Assessment Sponsor:   Gazi University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 18, 2023 Category: Research Source Type: clinical trials

Guanfacine for Hyperactivity in Children With Down Syndrome (HYPEbeGONE_DS)
Conditions:   Hyperactivity in Children With Down Syndrome;   Impulsivity in Children With Down Syndrome Interventions:   Drug: Guanfacine Hydrochloride Immediate Release;   Drug: Placebo Sponsors:   Rachel G. Greenberg, MD, MB, MHS;   The Emmes Company, LLC;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 18, 2023 Category: Research Source Type: clinical trials

Sensory Processing Skills in Toddler With Joint Hypermobility
Conditions:   Child Development;   Sensory Disorder;   Hypermobility, Joint Intervention:   Diagnostic Test: Assessment Sponsor:   Gazi University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 18, 2023 Category: Research Source Type: clinical trials

Guanfacine for Hyperactivity in Children With Down Syndrome (HYPEbeGONE_DS)
Conditions:   Hyperactivity in Children With Down Syndrome;   Impulsivity in Children With Down Syndrome Interventions:   Drug: Guanfacine Hydrochloride Immediate Release;   Drug: Placebo Sponsors:   Rachel G. Greenberg, MD, MB, MHS;   The Emmes Company, LLC;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 18, 2023 Category: Research Source Type: clinical trials

Sensory Processing Skills in Toddler With Joint Hypermobility
Conditions:   Child Development;   Sensory Disorder;   Hypermobility, Joint Intervention:   Diagnostic Test: Assessment Sponsor:   Gazi University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 18, 2023 Category: Research Source Type: clinical trials

Guanfacine for Hyperactivity in Children With Down Syndrome (HYPEbeGONE_DS)
Conditions:   Hyperactivity in Children With Down Syndrome;   Impulsivity in Children With Down Syndrome Interventions:   Drug: Guanfacine Hydrochloride Immediate Release;   Drug: Placebo Sponsors:   Rachel G. Greenberg, MD, MB, MHS;   The Emmes Company, LLC;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 18, 2023 Category: Research Source Type: clinical trials

Sensory Processing Skills in Toddler With Joint Hypermobility
Conditions:   Child Development;   Sensory Disorder;   Hypermobility, Joint Intervention:   Diagnostic Test: Assessment Sponsor:   Gazi University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 18, 2023 Category: Research Source Type: clinical trials

Guanfacine for Hyperactivity in Children With Down Syndrome (HYPEbeGONE_DS)
Conditions:   Hyperactivity in Children With Down Syndrome;   Impulsivity in Children With Down Syndrome Interventions:   Drug: Guanfacine Hydrochloride Immediate Release;   Drug: Placebo Sponsors:   Rachel G. Greenberg, MD, MB, MHS;   The Emmes Company, LLC;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 18, 2023 Category: Research Source Type: clinical trials

Sensory Processing Skills in Toddler With Joint Hypermobility
Conditions:   Child Development;   Sensory Disorder;   Hypermobility, Joint Intervention:   Diagnostic Test: Assessment Sponsor:   Gazi University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 18, 2023 Category: Research Source Type: clinical trials

Guanfacine for Hyperactivity in Children With Down Syndrome (HYPEbeGONE_DS)
Conditions:   Hyperactivity in Children With Down Syndrome;   Impulsivity in Children With Down Syndrome Interventions:   Drug: Guanfacine Hydrochloride Immediate Release;   Drug: Placebo Sponsors:   Rachel G. Greenberg, MD, MB, MHS;   The Emmes Company, LLC;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 18, 2023 Category: Research Source Type: clinical trials

Sensory Processing Skills in Toddler With Joint Hypermobility
Conditions:   Child Development;   Sensory Disorder;   Hypermobility, Joint Intervention:   Diagnostic Test: Assessment Sponsor:   Gazi University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 18, 2023 Category: Research Source Type: clinical trials

Guanfacine for Hyperactivity in Children With Down Syndrome (HYPEbeGONE_DS)
Conditions:   Hyperactivity in Children With Down Syndrome;   Impulsivity in Children With Down Syndrome Interventions:   Drug: Guanfacine Hydrochloride Immediate Release;   Drug: Placebo Sponsors:   Rachel G. Greenberg, MD, MB, MHS;   The Emmes Company, LLC;   Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 18, 2023 Category: Research Source Type: clinical trials

Sensory Processing Skills in Toddler With Joint Hypermobility
Conditions:   Child Development;   Sensory Disorder;   Hypermobility, Joint Intervention:   Diagnostic Test: Assessment Sponsor:   Gazi University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 18, 2023 Category: Research Source Type: clinical trials