Efficacy and Mechanisms of Dapagliflozin in Promoting Kidney Function and Cardiovascular Health in Kidney Transplant Recipients
Conditions: Kidney Transplant; Complications; Vascular Diseases; Diabetes Interventions: Drug: Dapagliflozin 10mg Tab; Drug: Placebo Sponsors: University of Colorado, Denver Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 20, 2023 Category: Research Source Type: clinical trials

REgiStry-based Cardiovascular qUality improvEment Research
Conditions: Percutaneous Coronary Intervention; Heart Failure; Cardiometabolic Syndrome; Structural Heart Abnormality Interventions: Behavioral: Cardiac rehabilitation; Other: Active post-market surveillance of devices; Other: Multi-omics approach to precision medicine; Other: The prescription pattern analysis Sponsors: Peking University Third Hospital; Peking University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 17, 2023 Category: Research Source Type: clinical trials

Anodal transcranial direct current stimulation associated with aerobic exercise on the functional and physical capacity of patients with heart failure with reduced ejection fraction: ELETRIC study protocol
DiscussionAlthough previous studies have investigated the combined effect of tDCS on T3 area and physical performance and have suggested that tDCS could have reduced ratings of perceived exertion by affecting the activity of the insular cortex, and therefore increase exercise tolerance, this study is the first to evaluate the effects of the addition of anodal tDCS to aerobic exercise training for improving physical and functional performance, decreasing the perceived exertion, altering the quantification of inflammatory cytokines, and improving the subclinical values of the cardiopulmonary test in patients with HFrEF, whic...
Source: Trials - November 17, 2023 Category: Research Source Type: clinical trials

Protocol update and baseline characteristics for the TRIal to slow the Progression of Diabetes (TRIPOD) randomized controlled trial
DiscussionThe final participant completed month 12 follow-up data collection on 8 June 2023. All pre-planned analyses will be conducted and final results reported.Trial registrationClinicalTrials.govNCT03800680. Registered on 11 January 2019. (Source: Trials)
Source: Trials - November 14, 2023 Category: Research Source Type: clinical trials

Effects of NT-0796 in Obese Participants at Risk of Cardiovascular Disease
Conditions: Cardiovascular Diseases Interventions: Drug: NT-0796 Sponsors: NodThera Limited Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 13, 2023 Category: Research Source Type: clinical trials