Optimization of cardiopulmonary bypass prime fluid to preserve microcirculatory perfusion during on-pump coronary artery bypass graft surgery: PRIME study protocol for a double-blind randomized trial
DiscussionPRIME is the first study to assess the effect of different prime fluid strategies on microcirculatory perfusion in cardiac surgery with CPB. If the results suggest that a specific crystalloid or colloid prime fluid strategy better preserves microcirculatory perfusion during on-pump cardiac surgery, the current study may help to find the optimal pump priming in cardiac surgery.Trial registrationClinicalTrials.gov NCT05647057. Registered on 04/25/2023. ClinicalTrials.gov PRS: Record Summary NCT05647057, all items can be found in the protocol. (Source: Trials)
Source: Trials - March 26, 2024 Category: Research Source Type: clinical trials
Transplanting Lungs From Uncontrolled Donation After Circulatory Death
Conditions: Lung Transplantation Interventions: Device: Lung uDCD Protocol Sponsors: NYU Langone Health; National Heart, Lung, and Blood Institute (NHLBI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 25, 2024 Category: Research Source Type: clinical trials
Thiamine Intervention and Coronary Artery Bypass Grafting
Conditions: Coronary Heart Disease; Coronary Artery Bypass Grafting Interventions: Dietary Supplement: Thiamine; Other: Placebo Sponsors: University of California, Los Angeles Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 25, 2024 Category: Research Source Type: clinical trials
Brain Heart InterActioNs in Cardiac Arrest. Ancillary Study of the HEAVENwARd Trial
Conditions: Cardiac Arrest Sponsors: CMC Ambroise Par é Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 25, 2024 Category: Research Source Type: clinical trials
Artificial Intelligence to Assist the Echocardiographic Identification of Transthyretin Cardiac Amyloidosis
Conditions: Amyloid Cardiomyopathy; Transthyretin Amyloid Cardiomyopathy; Transthyretin Cardiac Amyloidosis Interventions: Other: non interventional study Sponsors: Algalarrondo Vincent; Bichat Hospital; Bioquantis Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 25, 2024 Category: Research Source Type: clinical trials
Evaluation of Cirrhotic Cardiomyopathy by Cardiac MRI in Patients Waiting for Liver Transplant.
Conditions: Cirrhosis Interventions: Diagnostic Test: MRI; Biological: Blood sampling Sponsors: Centre Hospitalier Universitaire de Besancon Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 25, 2024 Category: Research Source Type: clinical trials
Research on Precision Pharmaceutical Care for Heart Transplant Recipients
Conditions: Heart Transplant Patients Sponsors: Nanjing First Hospital, Nanjing Medical University; Wuhan Union Hospital, China; Changhai Hospital; Shanghai Zhongshan Hospital Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 22, 2024 Category: Research Source Type: clinical trials
Exercise MRI to Evaluate Cardiorespiratory Fitness in Children With Heart Disease
Conditions: Pediatric ALL; Congenital Heart Disease; Heart Transplantation Interventions: Diagnostic Test: Exercise cardiac MRI Assessment; Diagnostic Test: Cardiopulmonary Exercise Test Sponsors: University of Alberta Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 22, 2024 Category: Research Source Type: clinical trials
ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing
Conditions: Arrhythmias, Cardiac; Atrioventricular Block; Reduced Systolic Function; Atrial Fibrillation; Bradyarrhythmia; Ventricular Tachycardia; Ventricular Dysfunction; Ventricular Fibrillation; Ventricular Arrythmia; Atrioventricular Nodal Disease; Atrioventricular Conduction Defects; Atrioventricular Block Complete; Atrioventricular Block Incomplete; Atrioventricular Junctional Rhythm; Bundle-Branch Block; Left Bundle-Branch Block; Heart Failure, Systolic; Block;Atrioventricular; Block; Arrhythmic; Block; Mobitz; Block, Heart; Block, Fascicular; Block Branch Bundle Left; Heart Failure ，Congestive; Heart Arrhythmia ...
Source: ClinicalTrials.gov - March 22, 2024 Category: Research Source Type: clinical trials
Role of Echocardiography in Optimization of Cardiac Catheterization in Children With Congenital Heart Disease
Conditions: Echocardiography Interventions: Other: echocardiography and percutaneous cardiac catheterization Sponsors: Assiut University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 22, 2024 Category: Research Source Type: clinical trials
Pharmacokinetics and Pharmacodynamics of Edoxaban Before and After Bariatric Surgery
Conditions: Bariatric Surgery Candidate Interventions: Drug: Edoxaban Pharmacokinetics and Pharmacodynamics Sponsors: Institut universitaire de cardiologie et de pneumologie de Qu ébec, University Laval Withdrawn (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 22, 2024 Category: Research Source Type: clinical trials
Using AI Text Messaging to Improve AHA's Life's Essential 8 Health Behaviors
Conditions: Cardiovascular Diseases; Lifestyle Factors Interventions: Behavioral: Generic text messages; Behavioral: Interactive AI chatbot text messaging; Behavioral: Proactive pharmacist support Sponsors: University of Colorado, Denver; National Heart, Lung, and Blood Institute (NHLBI) Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 22, 2024 Category: Research Source Type: clinical trials
Gap CO2 in Septic Patient to Predict Cardiomyopathy Septic
Conditions: Gap co2; Cardiac Output, Low; Cardiac Defect Interventions: Other: comparaison Sponsors: Mohammed VI University Hospital Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 22, 2024 Category: Research Source Type: clinical trials
Glycoxidation, Arterial Biomechanics, and Target Organ Damage
Conditions: Oxidative Stress; Cardiovascular Risk; Target Organ Damage Sponsors: Complejo Hospitalario Universitario de Santiago; Instituto de Investigaci ón Sanitaria de Santiago de Compostela; Instituto de Salud Carlos III; University of Santiago de Compostela; Hospital de Barbanza Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 22, 2024 Category: Research Source Type: clinical trials
Lymphedema, Low-grade Inflammation and the Vasculature in Turner Syndrome
Conditions: Turner Syndrome; Cardiovascular Diseases; Lymphedema; Inflammation Interventions: Other: No intervention other than obtaining biopsies; Drug: Indocyanine green (ICG) Sponsors: University of Aarhus; Aarhus University Hospital Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 22, 2024 Category: Research Source Type: clinical trials
