Low-carbohydrate diet in the treatment of type 2 diabetes mellitus (LoCaT): study protocol for a multicenter, randomized controlled trial
In this study, we aim to compare the effects of LCD and canagliflozin, a sodium-glucose cotransporter 2 inhibitor, in patients with T2DM.MethodsThis is a multicenter, randomized controlled trial. We will recruit 120 patients with poor-controlled T2DM. Participants will be randomly divided into canagliflozin and LCD groups in a 1:1 ratio. The primary outcome is the change in hemoglobin A1C levels after the 3-month intervention. The secondary outcomes are the time in range and cost of antihyperglycemic agents. Exploratory outcomes include physical examination, body composition, glucose variability, appetite, glycolipid metab...
Source: Trials - June 19, 2023 Category: Research Source Type: clinical trials

The effect of combined β-lactoglobulin supplementation and resistance exercise training prior to limb immobilisation on muscle protein synthesis rates in healthy young adults: study protocol for a randomised controlled trial
DiscussionThis novel study will establish the impact of a bimodal prehabilitation strategy that combines ß-lactoglobulin supplementation and resistance exercise training in modulating MPS following a short-term period of muscle disuse. If successful, this complex intervention may be translated to clinical practice with application to patients scheduled to undergo, for example, hip or knee replacement surgery.Trial registrationNCT05496452. Registered on August 10, 2022.Protocol version: 16-12-2022/1 (Source: Trials)
Source: Trials - June 13, 2023 Category: Research Source Type: clinical trials

Carbohydrate Rinsing and Caffeine Gum on Performance of Romanian Deadlifts Performance
Conditions:   Carbohydrate;   Caffeine Interventions:   Other: Carbohydrate mouth rinsing;   Other: 200 mg caffeine gum Sponsor:   National Taiwan Sport University Completed (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2023 Category: Research Source Type: clinical trials

Carbohydrate Beta Cell Function and Glucose Control in Children With Diabetes
Condition:   Diabetes Mellitus, Type 1 Interventions:   Other: Ketogenic diet, food delivery and education;   Other: Standard diet, food delivery and education Sponsors:   Boston Children's Hospital;   University of South Florida;   Indiana University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 12, 2023 Category: Research Source Type: clinical trials