Levels of anger in epilepsy patients treated with eslicarbazepine acetate - Toledo M, Mazuela G, Mauri JA, Rodriguez-Osorio X, G ómez-Eguilaz M, Castro-Vilanova D, Rodriguez-Uranga J, Santamarina E.
INTRODUCTION: Aggressive behavior is commonly associated with epilepsy and, can be influenced by the antiepileptic drugs (AEDs) taken. Sodium channel blockers, specifically the carboxamides derivatives carbamazepine and oxcarbazepine, are some of the AEDs ... (Source: SafetyLit)
Source: SafetyLit - April 8, 2019 Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Carbagen (carbamazepine) tablet supply issue
Information from the Department of Health and Social Care regarding Carbagen (carbamazepine) tablets supply issue.
Carbagen (Carbamazepine) various preparations
As carbamazepine is considered a Catego (Source: Royal Pharmaceutical Society News)
Source: Royal Pharmaceutical Society News - January 30, 2019 Category: Drugs & Pharmacology Source Type: news
Podcast: Lamotrigine versus carbamazepine monotherapy (single medication treatment) for epilepsy
Up to 70 million people worldwide have epilepsy and there are many Cochrane Reviews of ways to treat it. These include reviews that work with the original researchers to gather data on everyone who was in their studies, to perform individual participant data meta-analyses. In June 2018, Sarah Nevitt and colleagues from the University of Liverpool in the UK updated one of these reviews, comparing two commonly used drugs, lamotrigine and carbamazepine." Carbamazepine and lamotrigine are both recommended as first-line treatments for people with newly diagnosed focal onset epileptic seizures and as second-line treatments for t...
Source: Cochrane News and Events - December 18, 2018 Category: Information Technology Authors: Muriah Umoquit Source Type: news
Patient survival after acute voluntary poisoning with a huge dose of oxcarbazepine and olanzapine - Kalogera V, Galopoulos D, Eleftheriotis G, Meimeti E, Malios I, Marathonitis G, Loupa C.
INTRODUCTION: Oxcarbazepine is a carbamazepine pre-drug with less drug interactions. Its adverse effects, including hyponatremia, somnolence and ataxia, are dose dependent. Olanzapine is an atypical antipsychotic drug most commonly used to manage psychoses... (Source: SafetyLit)
Source: SafetyLit - December 8, 2018 Category: International Medicine & Public Health Tags: Poisoning Source Type: news
PixarBio CEO Faces Criminal Fraud Charges
In the latest turn of what has been one of the more peculiar medtech/biotech stories to develop over the past couple years, PixarBio CEO Frank Reynolds and two of his associates were arrested Tuesday on charges of securities fraud.
The arrest comes just shy of two months after PixarBio threatened to sue Reynolds' former company, InVivo Therapeutics, for libel and patent rights to the company's scaffold device.
The U.S. Attorney's Office for the District of Massachusetts said Tuesday that Reynolds, Jay Herod, and Kenneth Stromsland were charged with engaging in a scheme to defraud PixarBio investors by making false and misl...
Source: MDDI - April 25, 2018 Category: Medical Devices Authors: Amanda Pedersen Tags: Business Source Type: news
Feds arrest PixarBio CEO Reynolds on securities fraud charges
The bizarre saga of biotech executive Frank Reynolds took another turn today when federal authorities arrested the PixarBio (OTC:PXRB) CEO and two associates on securities fraud charges, claiming they misled investors about its opioid substitute and falsely claimed a $1 billion valuation.
PixarBio is purportedly developing a drug to replace morphine and other opiates, but prosecutors alleged that the product is actually an older anti-convulsant called carbamazepine, sold under the trade name Tegretol, that’s used to treat epilepsy and neuralgia; PixarBio plans to re-formulate the drug as a time-release injection calle...
Source: Mass Device - April 24, 2018 Category: Medical Devices Authors: Brad Perriello Tags: Drug-Device Combinations Legal News Wall Street Beat PixarBio Source Type: news
New Gene Test Reduces Skin Reactions to Carbamazepine New Gene Test Reduces Skin Reactions to Carbamazepine
A new gene variant test to guide treatment decisions led to reductions in the incidence of cutaneous adverse reactions to carbamazepine, a new study shows.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - April 5, 2018 Category: Consumer Health News Tags: Neurology & Neurosurgery News Source Type: news
Carnexiv (Carbamazepine Injection) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - December 15, 2017 Category: Drugs & Pharmacology Source Type: news
Tegretol (Carbamazepine) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - June 12, 2017 Category: Drugs & Pharmacology Source Type: news
What Causes Hyperammonemia?
Discussion
Reye’s syndrome (RS)is named for Dr. Douglas Reye who along with Drs. G. Morgan and J. Baral described encephalopathy and fatty accumulation and degeneration in children in a 1963 Lancet article. RS usually affects children but can occur at all ages. All organs can be affected but the liver and brain are primarily affected causing liver failure and encephalopathy as toxic metabolites (especially ammonia) accumulate, and intracranial hypertension and cerebral edema occurs. As the ammonia levels begin to rise (> 100 mg/dL) patients lose their appetite, have nausea and emesis and mental status changes whic...
Source: PediatricEducation.org - February 20, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
