Stronger together: Families of girls with SPG47 find support in each other
Imagine your child is diagnosed with a rare neurological condition. So rare that there are only a handful of reported cases, and those are from halfway around the world. This was the case for Chris and Kasey Edwards of Massachusetts and Kevin and Angela Duffy of Pennsylvania. Their daughters’, Robbie and Molly, are among only 11 children in the world to be diagnosed with an extremely rare genetic disorder, called spastic parapalegia-47 (SPG47). “When they told us how rare this was, our minds were going in a thousand directions,” says Kasey, Robbie’s mom. “We didn’t know what to think.&rd...
Source: Thrive, Children's Hospital Boston - December 20, 2016 Category: Pediatrics Authors: Ellen Greenlaw Tags: Diseases & Conditions Our Patients’ Stories Department of Neurology Dr. Basil Darras hereditary spastic parapalegia HSP type 47 living with rare disease SPG47 Source Type: news

2 women would rather have botox in their feet than give up stilettos
An increasing number of partygoers are having a combination of Botox and dermal fillers injected into the balls of their feet, which is claimed to make high stilettos as comfortable as flats. (Source: the Mail online | Health)
Source: the Mail online | Health - December 20, 2016 Category: Consumer Health News Source Type: news

Victoria Miller claims crippling headaches have been cured by Botox injections
Victoria Miller, 30, from Rochdale, Lancashire, struggled to find an effective treatment for her headaches. But she says 200 Botox injections have helped to get her life back on track. (Source: the Mail online | Health)
Source: the Mail online | Health - December 13, 2016 Category: Consumer Health News Source Type: news

The Anti-Aging Treatments Pain Scale You Need To Know About
For Allure, by Katie Becker. Discomfort and beauty are always in tension, so we teach ourselves the algorithm of: Is it worth it? We learn the calculations between ouch and better skin (or flatter abs, or a firmer jawline, or...). But you can't do the math without knowing what kind of pain you're in for. We went to the people who know best—the patients—to find out exactly what it feels like to be on the receiving end of all those needles, blades, and lasers. *Pain Meter runs on a scale of 1-5. Botox: An injectable neurotoxin used to temporarily paralyze facial muscles and smooth wrinkles The Patient Report: &q...
Source: Healthy Living - The Huffington Post - December 5, 2016 Category: Consumer Health News Source Type: news

Viper venom botox: the molecular origin and evolution of the waglerin peptides used in anti-wrinkle skin cream - Debono J, Xie B, Violette A, Fourmy R, Jaeger M, Fry BG.
The molecular origin of waglerin peptides has remained enigmatic despite their industrial application in skin cream products to paralyse facial muscles and thus reduce the incidence of wrinkles. Here we show that these neurotoxic peptides are the result of... (Source: SafetyLit)
Source: SafetyLit - November 30, 2016 Category: Global & Universal Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Botox injections: Can they relieve arthritis pain?
It's unclear whether Botox injections can help arthritis pain, but early studies are promising. (Source: MayoClinic.com - Ask a Specialist)
Source: MayoClinic.com - Ask a Specialist - November 29, 2016 Category: Consumer Health News Source Type: news

Botox-Type Drugs Can Treat Many Eye Conditions
(MedPage Today) -- A good approach when muscular dysfunction is the cause, expert says (Source: MedPage Today Meeting Coverage)
Source: MedPage Today Meeting Coverage - November 11, 2016 Category: Journals (General) Source Type: news

Turns Out, Faking A Smile Might Not Make You Happier After All
Perhaps you’ve heard that you can brighten your mood just by faking a smile. But that idea, which came out of a psychological experiment from the 1980s, may not be true after all, as scientists were not able to repeat the results in a lab setting in a large, rigorous new study. The hypothesis, called the facial-feedback hypothesis, dates back to a 1988 study in which participants rated the humor of cartoons while inadvertently mimicking either a smile or a pout. The participants were simply asked to hold a pen in their mouths, either with their lips (which pushes the face into a frown-like expression) or their t...
Source: Healthy Living - The Huffington Post - November 7, 2016 Category: Consumer Health News Source Type: news

What exactly IS botox and is it really safe? A doctor answers your pinching questions
Despite many fears about botox, Alison Bridges, a dermatologist from the Mayo Clinic, Minnesota, says Botulinum toxin is completely safe and you can stop at any time without any lasting effects. (Source: the Mail online | Health)
Source: the Mail online | Health - October 6, 2016 Category: Consumer Health News Source Type: news

Botox May Top Neuromodulation in Overactive Bladder Botox May Top Neuromodulation in Overactive Bladder
Episodes of urinary urgency were slightly lower after onabotulinumtoxinA injections, but the treatment led to more urinary tract infections and self-catheterizations in a randomized controlled trial.Medscape Medical News (Source: Medscape Medical News Headlines)
Source: Medscape Medical News Headlines - October 6, 2016 Category: Consumer Health News Tags: Urology News Source Type: news

Botox Beats Implant for Urinary Incontinence in Women
Title: Botox Beats Implant for Urinary Incontinence in WomenCategory: Health NewsCreated: 10/4/2016 12:00:00 AMLast Editorial Review: 10/5/2016 12:00:00 AM (Source: MedicineNet Womens Health General)
Source: MedicineNet Womens Health General - October 5, 2016 Category: OBGYN Source Type: news

Why BOTOX could be the best cure for female bladder incontinence - but it carries unpleasant side effects
Researchers at Duke University compared the standard nerve stimulation technique with the less common approach of injecting Botox into the bladder. To their surprise, Botox was more effective. (Source: the Mail online | Health)
Source: the Mail online | Health - October 5, 2016 Category: Consumer Health News Source Type: news

OnabotulinumtoxinA vs. Sacral Neuromodulation for Urgency Incontinence: No Clear Winner (FREE)
By Amy Orciari Herman Edited by David G. Fairchild, MD, MPH, and Lorenzo Di Francesco, MD, FACP, FHM OnabotulinumtoxinA (Botox) confers small improvements in urgency incontinence relative to sacral neuromodulation, but it also carries significant adverse effects, a JAMA … (Source: Physician's First Watch current issue)
Source: Physician's First Watch current issue - October 5, 2016 Category: Primary Care Source Type: news

Botox shots little better than nerve stimulation for incontinence
(Reuters Health) - Botox injections may be slightly better at reducing urinary incontinence in some older women than InterStim, an implanted bladder control device, results of a U.S. trial suggest. (Source: Reuters: Health)
Source: Reuters: Health - October 4, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

Botox Beats Implant for Urinary Incontinence in Women
But both have side effects that may affect your choice, researchers say (Source: WebMD Health)
Source: WebMD Health - October 4, 2016 Category: Consumer Health News Source Type: news

Botox beats implant for urinary urgency incontinence in women
Steven Reinberg, HealthDay News For women with bladder incontinence, Botox injections may help control leakage better than an implanted nerve stimulation device, a new study suggests. (Source: Health News - UPI.com)
Source: Health News - UPI.com - October 4, 2016 Category: Consumer Health News Source Type: news

Botox Beats Implant for Urinary Incontinence in Women
But both have side effects that may affect your choice, researchers say Source: HealthDay Related MedlinePlus Pages: Botox, Urinary Incontinence, Women's Health (Source: MedlinePlus Health News)
Source: MedlinePlus Health News - October 4, 2016 Category: Consumer Health News Source Type: news

Study compares treatments for urinary incontinence in women
Investigators assessed whether injection of onabotulinumtoxinA (Botox A) is superior to sacral neuromodulation (use of an implanted electrode for bladder control) in controlling episodes of refractory urgency urinary incontinence in women. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - October 4, 2016 Category: Science Source Type: news

Botox Beats Implant for Urinary Urgency Incontinence in Women
TUESDAY, Oct. 4, 2016 -- For women with bladder incontinence who haven't been helped by medications or other therapies, Botox injections may help control leakage better than an implanted nerve stimulation device, a new study suggests. However, both... (Source: Drugs.com - Daily MedNews)
Source: Drugs.com - Daily MedNews - October 4, 2016 Category: Journals (General) Source Type: news

Medical Tourism - A Growing Retail Heath Strategy
The Cleveland Clinic just announced plans to develop a hospital near Buckingham Palace in London. Cruise ship spas are now staffed by medical doctors and licensed acupuncturists. The United States once had the world's market share of in-bound patients seeking healthcare from "the best healthcare system in the world." Now that the U.S. is well-acknowledged to be the most expensive healthcare system in the world, medical tourism is both in-bound and, increasingly, out-bound, with at least 1.4 million Americans seeking healthcare abroad in 2016, according to Visa. Visa estimated that the U.S. out-bound healthcare m...
Source: Healthy Living - The Huffington Post - September 22, 2016 Category: Consumer Health News Source Type: news

MassDevice.com +5 | The top 5 medtech stories for September 21, 2016
Say hello to MassDevice +5, a bite-sized view of the top five medtech stories of the day. This feature of MassDevice.com’s coverage highlights our 5 biggest and most influential stories from the day’s news to make sure you’re up to date on the headlines that continue to shape the medical device industry. Get this in your inbox everyday by subscribing to our newsletters.   5. Levita Magnetics wins Class II status for gallbladder surgery device The FDA today announced that it reclassified Levita Magnetics’ magnetic surgical system, cleared for gallbladder removal surgeries, as a Class II device...
Source: Mass Device - September 21, 2016 Category: Medical Equipment Authors: MassDevice Tags: News Well Plus 5 Source Type: news

House committee probes FDA ’ s ‘ Botox police ’
A U.S. House committee launched a probe of the FDA’s criminal office, raising questions about the unit’s management and handling of cases involving devices, food and drugs. The U.S. House Energy & Commerce Committee told FDA commissioner Dr. Robert Califf that it’s “examining management concerns” and “possible morale concerns with the field offices” of the federal safety watchdog’s Office of Criminal Investigations. The Sept. 20 letter, signed by committee chairman Rep. Fred Upton (R-Mich.) and Rep. Tim Murphy (R-Pa.), chairman of the subcommittee on Oversi...
Source: Mass Device - September 21, 2016 Category: Medical Equipment Authors: Brad Perriello Tags: Food & Drug Administration (FDA) Regulatory/Compliance Capitol Hill FDA Office of Criminal Investigations Source Type: news

The bizarre rise of SCROTOX: Men are paying nearly £3,000 to have Botox in their private parts - so would you let your man do it? 
The treatment, which costs  £2,800, involves having botox injected into the testicles to decrease sweating, reduce wrinkles and make the scrotum appear larger due to muscles relaxing. (Source: the Mail online | Health)
Source: the Mail online | Health - September 21, 2016 Category: Consumer Health News Source Type: news

Allergan to buy Tobira in push for fatty liver disease drugs
(Reuters) - Botox maker Allergan Plc, in its third acquisition this month, said it would pay up to $1.7 billion for Tobira Therapeutics Inc to get a leg up in the race to develop therapies for NASH, an incurable fatty liver disease closely linked to obesity. (Source: Reuters: Health)
Source: Reuters: Health - September 21, 2016 Category: Consumer Health News Tags: healthNews Source Type: news

The 7 Hard Truths About Aging That Everyone Should Know
We’ve updated this post that ran a few years ago because, as we all know, every day is a new learning opportunity ― and we feel smarter now. Plus once in awhile, it’s good to share collective wisdom. Here are seven life lessons about aging worth being reminded of: 1. Small aches can sometimes be ignored.Growing older is not a pain-free process. Knees stiffen up. Feet sprout bunions. And fingers that once flew over the keyboard with the greatest of ease now sometimes cramp up. Most likely, none of this will kill you, which is why I say: Do your best to just keep moving. One of my biggest worrie...
Source: Healthy Living - The Huffington Post - September 11, 2016 Category: Consumer Health News Source Type: news

‘ Botox Police ’ : FDA crime unit draws fire over import crackdown
(Reuters) – On April 5, 2012, a criminal investigator from the Food and Drug Administration named Robert West charged into an oncology clinic in Greenville, Tennessee. West was chasing a lead that Dr. Anindya Sen and his wife, the clinic’s office manager Patricia Posey Sen, purchased an unapproved Turkish version of the cancer drug Avastin. But “Cowboy Bob,” as some defense attorneys call him, did not realize his interview was caught on the clinic’s surveillance cameras. West told Posey Sen she was guilty of buying counterfeit drugs and looked like a “deer in the headlights,” court...
Source: Mass Device - September 9, 2016 Category: Medical Equipment Authors: MassDevice Tags: Cosmetic/Aesthetic Food & Drug Administration (FDA) Source Type: news

Botox (Botulinum Toxin Type A) - updated on RxList
(Source: RxList - New and Updated Drug Monographs)
Source: RxList - New and Updated Drug Monographs - September 9, 2016 Category: Drugs & Pharmacology Source Type: news

​Allergan’s CEO pledges limited price hikes, says others have 'violated' social contract with big price increases
In response to public outcry over some drug companies that have drastically raised prices on medicines, the chief executive of Botox maker Allergan Plc pledged that his company would limit price increases on prescription drugs it makes. In a blog posting, CEO Brent Saunders called other drug companies that have engaged in price gouging “outliers” that are not only hurting patients but also harming investment and innovation. “The health care industry has had a long-standing unwritten social… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - September 7, 2016 Category: Pharmaceuticals Authors: I-Chun Chen Source Type: news

​Allergan’s CEO pledges limited price hikes, says others have 'violated' social contract with big price increases
In response to public outcry over some drug companies that have drastically raised prices on medicines, the chief executive of Botox maker Allergan Plc pledged that his company would limit price increases on prescription drugs it makes. In a blog posting, CEO Brent Saunders called other drug companies that have engaged in price gouging “outliers” that are not only hurting patients but also harming investment and innovation. “The health care industry has had a long-standing unwritten social… (Source: bizjournals.com Health Care:Biotechnology headlines)
Source: bizjournals.com Health Care:Biotechnology headlines - September 7, 2016 Category: Biotechnology Authors: I-Chun Chen Source Type: news

Confessions of a Female Plastic Surgeon
Image Source Celebrities are doing it, your co-workers are doing it, and even your inner circle is doing it. Your besties, however, are loath to admit they've had some "work" done. Is your colleague or friend looking a little younger these days? Or is that booty of theirs seeming just a little bit tighter all of a sudden? Trust me, it's not the Zumba classes, nor is it the juice cleanse they recently powered through. They've had something done - a bit of Botox, some liposuction, or maybe a facelift -- even if they vehemently deny it. According to Aviva Preminger, MD, a NYC female plastic surgeon, she's seen it al...
Source: Healthy Living - The Huffington Post - August 31, 2016 Category: Consumer Health News Source Type: news

3 Beauty-Boosting Benefits of Turmeric
by the Rodale's content team We're currently obsessed with turmeric. This powerful, brightly colored spice, extracted from the roots of plants in the ginger family, has been used for centuries in medicine, dyes, and an incalculable number of tasty meals. And these days, turmeric is really having a moment! That's because various current research studies have revealed the science behind the benefits of ingesting turmeric and its active ingredient, curcumin. Just a few of the health rewards these studies have linked the spice to are that it slows Alzheimer's progress, aids in detoxifying the liver and kidneys, and even boos...
Source: Healthy Living - The Huffington Post - August 30, 2016 Category: Consumer Health News Source Type: news

Botulinum neurotoxin in plastic surgery -- what's the evidence for effectiveness?
(Wolters Kluwer Health) Botox and other botulinum neurotoxin (BoNT) products are widely known for their use in treating facial wrinkles -- but they can also be used to treat a wide range of non-cosmetic problems. Eight conditions with good evidence of effective treatment with BoNT are identified in a special review in the August issue of Plastic and Reconstructive Surgery ® , the official medical journal of the American Society of Plastic Surgeons. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - August 30, 2016 Category: Global & Universal Source Type: news

Pharma Giant Finally Spending Its Money On Drugs, Not Tax Dodges
Pfizer went on a shopping spree this week, spending nearly $15.6 billion on two acquisitions to boost its array of cancer drugs and antibiotics. The Viagra maker on Monday bought Medivation for $14 billion, adding the San Francisco-based firm’s lucrative prostate cancer drug Xtandi to its roster of oncology treatments. On Wednesday, the company announced the purchase of U.K. rival AstraZeneca’s antibiotics division for $1.575 billion plus royalties to bolster a part of Pfizer’s business that’s been hurt by expired patents. The deals mark a departure from Pfizer’s attempts in the last two ...
Source: Healthy Living - The Huffington Post - August 24, 2016 Category: Consumer Health News Source Type: news

Pharma Giant Finally Spending Its Money On Drugs, Not Tax Dodges
Pfizer went on a shopping spree this week, spending nearly $15.6 billion on two acquisitions to boost its array of cancer drugs and antibiotics. The Viagra maker on Monday bought Medivation for $14 billion, adding the San Francisco-based firm’s lucrative prostate cancer drug Xtandi to its roster of oncology treatments. On Wednesday, the company announced the purchase of U.K. rival AstraZeneca’s antibiotics division for $1.575 billion plus royalties to bolster a part of Pfizer’s business that’s been hurt by expired patents. The deals mark a departure from Pfizer’s attempts in the last two ...
Source: Science - The Huffington Post - August 24, 2016 Category: Science Source Type: news

3 Reasons You Might Sweat So Much -- And What To Do About It
1. Your Mom, Uncle or Third Cousin Sweat a Lot TooThere’s a type of excessive sweating that runs in families called primary hyperhidrosis (PH). Experts don’t know what causes it, but it’s definitely not because you have more sweat glands or that they’re supersized. The size, number and location of these glands appear totally normal in people with PH, says Dee Anna Glaser, MD, professor of dermatology at Saint Louis University School of Medicine and president of the International Hyperhidrosis Society. Their best guess: Something’s off with your body’s autonomic nervous system, which cont...
Source: Healthy Living - The Huffington Post - August 23, 2016 Category: Consumer Health News Source Type: news

Allergan Revenue Increases, Though Loss Widens
Allergan posted revenue growth, but its loss doubled in its latest quarter as the Botox maker moves on from the sale of its generics business to Teva Pharmaceutical Industries and its failed $150 billion merger with Pfizer. (Source: WSJ.com: Health)
Source: WSJ.com: Health - August 9, 2016 Category: Pharmaceuticals Tags: PAID Source Type: news

Paralyzing toxins in Botox 'DO spread to other parts of your body
The age-defying injection was approved by the FDA in 2002 on the grounds that its muscle-freezing chemicals would not move from the injection site. But new tests have shown it can venture elsewhere. (Source: the Mail online | Health)
Source: the Mail online | Health - August 8, 2016 Category: Consumer Health News Source Type: news

Botox for Migraines?
I suffer from migraines and considered treatment with Botox a few years ago but was discouraged after I was told it wouldn't help for very long. Now I hear it works better. True? (Source: Dr. Weil Q and A)
Source: Dr. Weil Q and A - August 5, 2016 Category: Consumer Health News Source Type: news

Regulator backs register for nurses providing Botox
An independent quality mark for nurses involved in giving injectable cosmetics, such as Botox, has been rubberstamped today by regulators. (Source: Nursing Times)
Source: Nursing Times - August 1, 2016 Category: Nursing Source Type: news

Vensica Medical Completes $500,000 Finance Round
MISGAV, Israel, July 19, 2016 -- (Healthcare Sales & Marketing Network) -- Vensica Medical, a portfolio company of Trendlines Medical, announced the completion of a financing round of US$500,000 from a private foreign investor. Vensica is developing a ne... Devices, Drug Delivery, Urology, Venture CapitalVensica Medical, overactive bladder, Botox (Source: HSMN NewsFeed)
Source: HSMN NewsFeed - July 19, 2016 Category: Pharmaceuticals Source Type: news

Woman who wants to be 'as fake as possible' spends £100,000 on cosmetic surgery
The British woman, named only as Star, has had two boob jobs to go from a 32A to a 32E, a nose job, liposuction on her legs, Botox injections and lip fillers. She appeared on E! show Botched. (Source: the Mail online | Health)
Source: the Mail online | Health - July 14, 2016 Category: Consumer Health News Source Type: news

Celebrities reject Botox and face lifts in favour of the natural look
The 'frozen face' is out of fashion as stars embrace a more natural appearance, says Dr Benji Dhillon who reveals that improved techniques and laser treatments give a more subtle look. (Source: the Mail online | Health)
Source: the Mail online | Health - July 7, 2016 Category: Consumer Health News Source Type: news

Botox and Dystonia
LAS VEGAS, Nev. (Ivanhoe Newswire) -- Long before it wiped out worry lines and age wrinkles, Botox was originally created to stop muscle spasms in the eye. Besides its fountain-of-youth qualities, it’s being used to relieve exhausting and sometimes debilitating effects of a neurological disorder called dystonia. (Source: Medical Headlines From Ivanhoe.com)
Source: Medical Headlines From Ivanhoe.com - July 5, 2016 Category: Consumer Health News Source Type: news

'Why at 63-years-old, I’m turning my back on botox'
Although Anna Quindlen is almost 64, she has no idea whether she looks it. But, she says, her business is telling stories and her face tells one. Therefore she just can't bear to edit it too much. (Source: the Mail online | Health)
Source: the Mail online | Health - June 20, 2016 Category: Consumer Health News Source Type: news

From IPO to M&A: 3 recent tales of Bay Area biotech ups and downs
Is the biotech bubble blowing up in the faces of a few Bay Area life sciences companies? It depends on how you look at a trio of companies' recent news. After a 2014-15 run that minted 32 public companies regionally and raised close to $3 billion, three of those IPO companies this week showed that it's not all happy days. Revance Therapeutics shifted gears after its topical version of Botox failed a late-stage study, Corium International Inc. will lay off 17 percent of its workforce to zero in on… (Source: bizjournals.com Health Care:Pharmaceuticals headlines)
Source: bizjournals.com Health Care:Pharmaceuticals headlines - June 17, 2016 Category: Pharmaceuticals Authors: Ron Leuty Source Type: news

Botox's sweet tooth underlies its key neuron-targeting mechanism
The Botox toxin has a sweet tooth, and it's this craving for sugars -- glycans, to be exact -- that underlies its extreme ability target neuron cells in the body, while giving researchers an approach to neutralize it. (Source: ScienceDaily Headlines)
Source: ScienceDaily Headlines - June 13, 2016 Category: Science Source Type: news

The best age to have a healthy baby? 25, says doctor who warns older women they can't 'Botox their ovaries'
Dr Gillian Lockwood, medical director of the Midland Fertility Clinic, said the pressures of modern life meant many delayed childbirth but women should start families earlier. (Source: the Mail online | Health)
Source: the Mail online | Health - June 13, 2016 Category: Consumer Health News Source Type: news

Botox's sweet tooth underlies its key neuron-targeting mechanism
(University of California - Irvine) The Botox toxin has a sweet tooth, and it's this craving for sugars -- glycans, to be exact -- that underlies its extreme ability target neuron cells in the body ... while giving researchers an approach to neutralize it. (Source: EurekAlert! - Medicine and Health)
Source: EurekAlert! - Medicine and Health - June 13, 2016 Category: Global & Universal Source Type: news

BOTOX Injections
Botox (Source: eMedicineHealth.com)
Source: eMedicineHealth.com - June 1, 2016 Category: Journals (General) Source Type: news