TWiV 485: Fishing with defective flies
The TWiV posse considers viral insulin-like peptides encoded in fish genomes, and insect antiviral immunity by production of viral DNA from defective genomes of RNA viruses. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker Become a patron of TWiV! Links for this episode ASM Microbe 2018 Insulin-like peptides in Iridovirus genomes (PNAS) Dicer-2 dependent generation of cvDNA from defective genomes (Cell Host Micr) Carla Saleh on insect antiviral immunity (TWiV 301) RNAseIII ancient antiviral RNA platform (TWiV 450) cvDNA precursor to EVEs (TWiV 482) Image credit: Paul Young L...
Source: This Week in Virology - MP3 Edition - March 18, 2018 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
The ABCD ’s of CB5T
Today’s post is about the Cybernetic Big Five Theory (CB5T) theory of personality structure [pdf and pdf] as proposed by Colin DeYoung et al.
Colin and colleagues have proposed a structure of personality that is hierarchical and is build around the popular Big Five traits of Neuroticism, Extraversion, Openness/Intellect, Conscientiousness and Agreeableness.
English: A diagram to illustrate the layout of a hierarchical organisation. (Photo credit: Wikipedia)
The top level of the hierarchy consists of metatraits of Stability and Plasticity also called Alpha and Beta. Stability is related to the shared variance between...
Source: The Mouse Trap - March 10, 2018 Category: Psychiatry & Psychology Authors: sandygautam Tags: personality ABCD model Big Five personality traits CB5T Source Type: podcasts
Michael Graziano explains Peripersonal Neurons (BS 142)
Michael Graziano (Click image to play audio)
As a young student Dr. Michael Graziano helped discover peripersonal neurons, which are neurons that detect when objects are coming near our bodies. In his new book The Spaces Between Us: A Story of Neuroscience, Evolution, and Human Nature, Graziano takes us through two decades of research into how these neurons work. Peripersonal neurons make it possible for us to move through our lives without constantly bumping into the objects and people around us, but because they work outside our conscious awareness we take them for granted. Graziano &nbs...
Source: the Brain Science Podcast and Blog with Dr. Ginger Campbell - February 23, 2018 Category: Neuroscience Authors: Ginger Campbell, MD Tags: Body maps Books Brain Research Embodiment Mirror Neurons Podcast Show Notes Source Type: podcasts
Michael Graziano explains Peripersonal Neurons (BS 142)
Michael Graziano (Click image to play audio)
As a young student Dr. Michael Graziano helped discover peripersonal neurons, which are neurons that detect when objects are coming near our bodies. In his new book The Spaces Between Us: A Story of Neuroscience, Evolution, and Human Nature, Graziano takes us through two decades of research into how these neurons work. Peripersonal neurons make it possible for us to move through our lives without constantly bumping into the objects and people around us, but because they work outside our conscious awareness we take them for granted. Graziano &nbs...
Source: the Brain Science Podcast and Blog with Dr. Ginger Campbell - February 23, 2018 Category: Neuroscience Authors: Ginger Campbell, MD Tags: Body maps Books Brain Research Embodiment Mirror Neurons Podcast Show Notes Source Type: podcasts
TWiV 481: And biles to go before I delete
The TWiVodrome considers the intestinal tract as an alternative infection route for MERS coronavirus, and how reduced accumulation of defective viral RNAs might lead to severe influenza. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Become a patron of TWiV! Links for this episode HaHa influenza virus (mBio) MERS coronavirus intestinal transmission (Sci Adv) Simulated gastric and intestinal fluids Stomacher Defective genomes and severe influenza (PLoS Path) Image credit Letters read on TWiV 481 Weekly Science Picks Kathy - CD45.1 and CD45.2 mice may not be functionally eq...
Source: This Week in Virology - MP3 Edition - February 18, 2018 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
TWiV 479: Trypsin the flight fantastic
The TWiVome explores induction of antiviral responses by repeating patterns of capsids, and a fungus in the mosquito gut that aids dengue virus replication. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Become a patron of TWiV! Links for this episode Innate immune detection of capsid patterns (mBio) Mosquito gut fungus aids dengue virus replication (eLife) Nominate MicrobeTV for a Keck award Image credit Letters read on TWiV 479 Weekly Science Picks Kathy - Great Lakes, false color Rich - Times 360 Lego factory tour Dickson - 3D printed houses Alan - The new terms for tr...
Source: This Week in Virology - MP3 Edition - February 4, 2018 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
Rodrigo Quian Quiroga: Memory and Perception (BS 141)
Rodrigo Quian Quiroga (Right click to listen)
Neuroscientist Rodrigo Quian Quiroga has written a wonderfully accessible book called The Forgetting Machine: Memory, Perception, and the "Jennifer Aniston Neuron. " I interviewed him for BS 141 because I wanted to hear the real science behind his work. The key idea of his book his that perception and memory are based on similar principles. Our perceptions are largely created by our brains, but the same is also true for our memories.Our memories are dynamically recreated with each recall. This has important and surprising implications. We also ...
Source: the Brain Science Podcast and Blog with Dr. Ginger Campbell - January 25, 2018 Category: Neuroscience Authors: Ginger Campbell, MD Tags: Interviews Podcast Show Notes Memory Source Type: podcasts
Rodrigo Quian Quiroga: Memory and Perception (BS 141)
Rodrigo Quian Quiroga (Right click to listen)
Neuroscientist Rodrigo Quian Quiroga has written a wonderfully accessible book called The Forgetting Machine: Memory, Perception, and the "Jennifer Aniston Neuron. " I interviewed him for BS 141 because I wanted to hear the real science behind his work. The key idea of his book his that perception and memory are based on similar principles. Our perceptions are largely created by our brains, but the same is also true for our memories.Our memories are dynamically recreated with each recall. This has important and surprising implications. We also ...
Source: the Brain Science Podcast and Blog with Dr. Ginger Campbell - January 25, 2018 Category: Neuroscience Authors: Ginger Campbell, MD Tags: Interviews Podcast Show Notes Memory Source Type: podcasts
Brain Science Review of 2017 (BS 140)
Discussion of Language at the Speed of Sight: How We Read, Why So Many Can’t, and What Can Be Done About It by Mark Seidenberg BS 137 Seth Grant presents evidence that brain development follows a genetic calendarBS 138 John Medina explores Brain Rules for Aging WellBS 139 Jeff Hawkins discusses modeling cortical functionEven the episodes that sound technical are accessible to listeners of all backgrounds.
How to get this episode:FREE: audio mp3 (click to stream, right click to download)Episode Transcript [Coming Soon]Premium Subscribers have unlimited access to ALL old episodes and transcripts, as...
Source: the Brain Science Podcast and Blog with Dr. Ginger Campbell - December 22, 2017 Category: Neuroscience Authors: Ginger Campbell, MD Source Type: podcasts
Brain Science Review of 2017 (BS 140)
Discussion of Language at the Speed of Sight: How We Read, Why So Many Can’t, and What Can Be Done About It by Mark SeidenbergBS 137 Seth Grant presents evidence that brain development follows a genetic calendarBS 138 John Medina explores Brain Rules for Aging WellBS 139 Jeff Hawkins discusses modeling cortical functionEven the episodes that sound technical are accessible to listeners of all backgrounds.
How to get this episode:FREE: audio mp3 (click to stream, right click to download)Episode Transcript [Buy for $2]Premium Subscribers have unlimited access to ALL old episodes and transcripts, as well as extra content ...
Source: the Brain Science Podcast and Blog with Dr. Ginger Campbell - December 22, 2017 Category: Neuroscience Authors: Ginger Campbell, MD Tags: Neuroscience Podcast Show Notes Source Type: podcasts
An Unusually Happy Holiday Blog from 'Scrooge'
Dr Lundberg offers an atypically celebratory holiday message about the world ' s first free, for-credit university, NextGenU. (Source: Medscape Internal Medicine Podcast)
Source: Medscape Internal Medicine Podcast - December 19, 2017 Category: Internal Medicine Authors: Medscape Source Type: podcasts
Welcoming the One Millionth Reader
I know its a bit premature (the blog visit count on my blog is only about 99,8000 yet and it will take another 2-3 days to hit that milestone) but I wanted to take this opportunity to thank all the ~1 million readers who have thought it worthwhile to visit my blog at least once. You know who who you are: thanks to the Moms and the Grandmoms (those readers who were the only ones to visit it in the early days) and thanks also to the Siblings and Cousins (those blogs which encouraged, accepted and sometimes generated a healthy sibling competition of sorts in the early days?).
Maker Faire 2008, San Mateo – a life size ve...
Source: The Mouse Trap - December 11, 2017 Category: Psychiatry & Psychology Authors: sandygautam Tags: Blog blogs personal blogging Source Type: podcasts
Jeff Hawkins Explores a New Theory of Cortical Function
Jeff Hawkins (Click to play interview)
My Brain Science podcast was partially inspired by Jeff Hawkins bestseller On Intelligence, so I am very pleased to post a new interview (BS 139) in which we discuss the exciting work he has been doing at Numenta. Hawkins is committed to understanding how the neocortex generates intelligence and he feels that his latest paper marks an important landmark in that work.We started our conversation by discussing some of the work that Hawkins published in 2016 including two key papers. One presents a new model of the neuron that incorporates active dendrite...
Source: the Brain Science Podcast and Blog with Dr. Ginger Campbell - November 27, 2017 Category: Neuroscience Authors: Ginger Campbell, MD Tags: Artificial Intelligence Brain Research Cognitive Science Computation Interviews Neuroscience Podcast Show Notes Source Type: podcasts
Jeff Hawkins Explores a New Theory of Cortical Function (BS 139)
Jeff Hawkins (Click to play interview)
My Brain Science podcast was partially inspired by Jeff Hawkins bestseller On Intelligence, so I am very pleased to post a new interview (BS 139) in which we discuss the exciting work he has been doing at Numenta. Hawkins is committed to understanding how the neocortex generates intelligence and he feels that his latest paper marks an important landmark in that work.We started our conversation by discussing some of the work that Hawkins published in 2016 including two key papers. One presents a new model of the neuron that incorporates active dendrite...
Source: the Brain Science Podcast and Blog with Dr. Ginger Campbell - November 27, 2017 Category: Neuroscience Authors: Ginger Campbell, MD Tags: Artificial Intelligence Brain Research Cognitive Science Computation Interviews Neuroscience Podcast Show Notes Source Type: podcasts
TWiV 468: Zika by the slice
Amy joins the TWiV team to talk about her career and her work on Zika virus neurotropism using embryonic mouse organotypic brain slice cultures. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Kathy Spindler Guest: Amy Rosenfeld Become a patron of TWiV! Links for this episode Grad students face tax hike (Nature) House voted to bankrupt grad students (NYTimes) Neurotropism of early and late Zika virus isolates (PNAS) Zika virus blocks the neuron road (virology blog) Letters read on TWiV 468 This episode is brought to you by the Department of Microbiology at the Icahn School of Medicin...
Source: This Week in Virology - MP3 Edition - November 19, 2017 Category: Virology Authors: Vincent Racaniello Source Type: podcasts
