Benzonatate Overdose Presenting as Cardiac Arrest with Rapidly Narrowing QRS Interval
We report a case of a patient presenting following a benzonatate overdose with a prolonged QRS on her initial electrocardiograph (ECG) rhythm strip with rapid normalization of QRS duration.CASE REPORT: A 14-year-old girl presented in cardiac arrest following a benzonatate overdose. The patient was found in cardiac arrest within minutes of last being known well. Bystanders immediately provided cardiopulmonary resuscitation (CPR), and she was in asystole on emergency medical services (EMS) arrival. Return of spontaneous circulation (ROSC) was obtained following administration of intraosseous epinephrine and naloxone. EMS obt...
Source: Journal of Medical Toxicology - July 5, 2022 Category: Toxicology Authors: Robert J Stephens Ari B Filip Kevin T Baumgartner Evan S Schwarz David B Liss Source Type: research

Benzonatate Overdose Presenting as Cardiac Arrest with Rapidly Narrowing QRS Interval
We report a case of a patient presenting following a benzonatate overdose with a prolonged QRS on her initial electrocardiograph (ECG) rhythm strip with rapid normalization of QRS duration.CASE REPORT: A 14-year-old girl presented in cardiac arrest following a benzonatate overdose. The patient was found in cardiac arrest within minutes of last being known well. Bystanders immediately provided cardiopulmonary resuscitation (CPR), and she was in asystole on emergency medical services (EMS) arrival. Return of spontaneous circulation (ROSC) was obtained following administration of intraosseous epinephrine and naloxone. EMS obt...
Source: Journal of Medical Toxicology - July 5, 2022 Category: Toxicology Authors: Robert J Stephens Ari B Filip Kevin T Baumgartner Evan S Schwarz David B Liss Source Type: research

Benzonatate Overdose Presenting as Cardiac Arrest with Rapidly Narrowing QRS Interval
We report a case of a patient presenting following a benzonatate overdose with a prolonged QRS on her initial electrocardiograph (ECG) rhythm strip with rapid normalization of QRS duration.CASE REPORT: A 14-year-old girl presented in cardiac arrest following a benzonatate overdose. The patient was found in cardiac arrest within minutes of last being known well. Bystanders immediately provided cardiopulmonary resuscitation (CPR), and she was in asystole on emergency medical services (EMS) arrival. Return of spontaneous circulation (ROSC) was obtained following administration of intraosseous epinephrine and naloxone. EMS obt...
Source: Journal of Medical Toxicology - July 5, 2022 Category: Toxicology Authors: Robert J Stephens Ari B Filip Kevin T Baumgartner Evan S Schwarz David B Liss Source Type: research

Benzonatate Overdose Presenting as Cardiac Arrest with Rapidly Narrowing QRS Interval
We report a case of a patient presenting following a benzonatate overdose with a prolonged QRS on her initial electrocardiograph (ECG) rhythm strip with rapid normalization of QRS duration.CASE REPORT: A 14-year-old girl presented in cardiac arrest following a benzonatate overdose. The patient was found in cardiac arrest within minutes of last being known well. Bystanders immediately provided cardiopulmonary resuscitation (CPR), and she was in asystole on emergency medical services (EMS) arrival. Return of spontaneous circulation (ROSC) was obtained following administration of intraosseous epinephrine and naloxone. EMS obt...
Source: Journal of Medical Toxicology - July 5, 2022 Category: Toxicology Authors: Robert J Stephens Ari B Filip Kevin T Baumgartner Evan S Schwarz David B Liss Source Type: research

Benzonatate Overdose Presenting as Cardiac Arrest with Rapidly Narrowing QRS Interval
We report a case of a patient presenting following a benzonatate overdose with a prolonged QRS on her initial electrocardiograph (ECG) rhythm strip with rapid normalization of QRS duration.CASE REPORT: A 14-year-old girl presented in cardiac arrest following a benzonatate overdose. The patient was found in cardiac arrest within minutes of last being known well. Bystanders immediately provided cardiopulmonary resuscitation (CPR), and she was in asystole on emergency medical services (EMS) arrival. Return of spontaneous circulation (ROSC) was obtained following administration of intraosseous epinephrine and naloxone. EMS obt...
Source: Journal of Medical Toxicology - July 5, 2022 Category: Toxicology Authors: Robert J Stephens Ari B Filip Kevin T Baumgartner Evan S Schwarz David B Liss Source Type: research

Benzonatate Overdose Presenting as Cardiac Arrest with Rapidly Narrowing QRS Interval
We report a case of a patient presenting following a benzonatate overdose with a prolonged QRS on her initial electrocardiograph (ECG) rhythm strip with rapid normalization of QRS duration.CASE REPORT: A 14-year-old girl presented in cardiac arrest following a benzonatate overdose. The patient was found in cardiac arrest within minutes of last being known well. Bystanders immediately provided cardiopulmonary resuscitation (CPR), and she was in asystole on emergency medical services (EMS) arrival. Return of spontaneous circulation (ROSC) was obtained following administration of intraosseous epinephrine and naloxone. EMS obt...
Source: Journal of Medical Toxicology - July 5, 2022 Category: Toxicology Authors: Robert J Stephens Ari B Filip Kevin T Baumgartner Evan S Schwarz David B Liss Source Type: research

Benzonatate Overdose Presenting as Cardiac Arrest with Rapidly Narrowing QRS Interval
We report a case of a patient presenting following a benzonatate overdose with a prolonged QRS on her initial electrocardiograph (ECG) rhythm strip with rapid normalization of QRS duration.CASE REPORT: A 14-year-old girl presented in cardiac arrest following a benzonatate overdose. The patient was found in cardiac arrest within minutes of last being known well. Bystanders immediately provided cardiopulmonary resuscitation (CPR), and she was in asystole on emergency medical services (EMS) arrival. Return of spontaneous circulation (ROSC) was obtained following administration of intraosseous epinephrine and naloxone. EMS obt...
Source: Journal of Medical Toxicology - July 5, 2022 Category: Toxicology Authors: Robert J Stephens Ari B Filip Kevin T Baumgartner Evan S Schwarz David B Liss Source Type: research

Benzonatate Overdose Presenting as Cardiac Arrest with Rapidly Narrowing QRS Interval
We report a case of a patient presenting following a benzonatate overdose with a prolonged QRS on her initial electrocardiograph (ECG) rhythm strip with rapid normalization of QRS duration.CASE REPORT: A 14-year-old girl presented in cardiac arrest following a benzonatate overdose. The patient was found in cardiac arrest within minutes of last being known well. Bystanders immediately provided cardiopulmonary resuscitation (CPR), and she was in asystole on emergency medical services (EMS) arrival. Return of spontaneous circulation (ROSC) was obtained following administration of intraosseous epinephrine and naloxone. EMS obt...
Source: Journal of Medical Toxicology - July 5, 2022 Category: Toxicology Authors: Robert J Stephens Ari B Filip Kevin T Baumgartner Evan S Schwarz David B Liss Source Type: research

Benzonatate Overdose Presenting as Cardiac Arrest with Rapidly Narrowing QRS Interval
We report a case of a patient presenting following a benzonatate overdose with a prolonged QRS on her initial electrocardiograph (ECG) rhythm strip with rapid normalization of QRS duration.CASE REPORT: A 14-year-old girl presented in cardiac arrest following a benzonatate overdose. The patient was found in cardiac arrest within minutes of last being known well. Bystanders immediately provided cardiopulmonary resuscitation (CPR), and she was in asystole on emergency medical services (EMS) arrival. Return of spontaneous circulation (ROSC) was obtained following administration of intraosseous epinephrine and naloxone. EMS obt...
Source: Journal of Medical Toxicology - July 5, 2022 Category: Toxicology Authors: Robert J Stephens Ari B Filip Kevin T Baumgartner Evan S Schwarz David B Liss Source Type: research

Benzonatate Overdose Presenting as Cardiac Arrest with Rapidly Narrowing QRS Interval
We report a case of a patient presenting following a benzonatate overdose with a prolonged QRS on her initial electrocardiograph (ECG) rhythm strip with rapid normalization of QRS duration.CASE REPORT: A 14-year-old girl presented in cardiac arrest following a benzonatate overdose. The patient was found in cardiac arrest within minutes of last being known well. Bystanders immediately provided cardiopulmonary resuscitation (CPR), and she was in asystole on emergency medical services (EMS) arrival. Return of spontaneous circulation (ROSC) was obtained following administration of intraosseous epinephrine and naloxone. EMS obt...
Source: Journal of Medical Toxicology - July 5, 2022 Category: Toxicology Authors: Robert J Stephens Ari B Filip Kevin T Baumgartner Evan S Schwarz David B Liss Source Type: research

Benzonatate Overdose Presenting as Cardiac Arrest with Rapidly Narrowing QRS Interval
We report a case of a patient presenting following a benzonatate overdose with a prolonged QRS on her initial electrocardiograph (ECG) rhythm strip with rapid normalization of QRS duration.CASE REPORT: A 14-year-old girl presented in cardiac arrest following a benzonatate overdose. The patient was found in cardiac arrest within minutes of last being known well. Bystanders immediately provided cardiopulmonary resuscitation (CPR), and she was in asystole on emergency medical services (EMS) arrival. Return of spontaneous circulation (ROSC) was obtained following administration of intraosseous epinephrine and naloxone. EMS obt...
Source: Journal of Medical Toxicology - July 5, 2022 Category: Toxicology Authors: Robert J Stephens Ari B Filip Kevin T Baumgartner Evan S Schwarz David B Liss Source Type: research

Benzonatate Overdose Presenting as Cardiac Arrest with Rapidly Narrowing QRS Interval
We report a case of a patient presenting following a benzonatate overdose with a prolonged QRS on her initial electrocardiograph (ECG) rhythm strip with rapid normalization of QRS duration.CASE REPORT: A 14-year-old girl presented in cardiac arrest following a benzonatate overdose. The patient was found in cardiac arrest within minutes of last being known well. Bystanders immediately provided cardiopulmonary resuscitation (CPR), and she was in asystole on emergency medical services (EMS) arrival. Return of spontaneous circulation (ROSC) was obtained following administration of intraosseous epinephrine and naloxone. EMS obt...
Source: Journal of Medical Toxicology - July 5, 2022 Category: Toxicology Authors: Robert J Stephens Ari B Filip Kevin T Baumgartner Evan S Schwarz David B Liss Source Type: research

A Survey of Provider-Reported Use and Perceived Effectiveness of Medications for Symptom Management in Telemedicine and Outpatient Visits for Mild COVID-19
ConclusionsProviders reported that clinical care of mild COVID-19 with medications in common use for other respiratory infections is effective, both at episodic care and longitudinal sites of care, but that specific symptoms are still challenging to manage. (Source: Infectious Diseases and Therapy)
Source: Infectious Diseases and Therapy - March 22, 2021 Category: Infectious Diseases Source Type: research

Development and Validation of LC-MS method for the determination of Heptaethylene glycol monomethyl ether in Benzonatate bulk drugs
Biomed Chromatogr. 2021 Feb 19:e5096. doi: 10.1002/bmc.5096. Online ahead of print.ABSTRACTA simple and isocratic reverse-phase liquid chromatography with mass spectrometric method has been developed and validated for the determination of Heptaethylene glycol monomethyl ether in Benzonatate drug substance. Benzonatate is an oral antitussive drug used to relieve and suppress cough in patients older than ten years of age. The presence of residual Heptaethylene glycol monomethyl ether in Benzonatate drug substance shall affect the safety, strength, purity, and quality of the drug substance. The subject compound separation was...
Source: Biomedical Chromatography : BMC - February 19, 2021 Category: Biomedical Science Authors: Lakshmi Narasimha Rao Katakam Santhosh Kumar Ettaboina Vishnu Murthy Marisetti Source Type: research

Development and Validation of LC-MS method for the determination of Heptaethylene glycol monomethyl ether in Benzonatate bulk drugs.
Abstract A simple and isocratic reverse-phase liquid chromatography with mass spectrometric method has been developed and validated for the determination of Heptaethylene glycol monomethyl ether in Benzonatate drug substance. Benzonatate is an oral antitussive drug used to relieve and suppress cough in patients older than ten years of age. The presence of residual Heptaethylene glycol monomethyl ether in Benzonatate drug substance shall affect the safety, strength, purity, and quality of the drug substance. The subject compound separation was achieved using 0.1% formic acid and acetonitrile (50:50 v/v) at ...
Source: Biomedical Chromatography : BMC - February 19, 2021 Category: Biomedical Science Authors: Katakam LNR, Ettaboina SK, Marisetti VM Tags: Biomed Chromatogr Source Type: research