HEAL Initiative: Integrated Approach to Pain and Opioid Use in Hemodialysis Patients: The Hemodialysis Opioid Prescription Effort (HOPE) Consortium - Scientific and Data Research Center (U01 Clinical Trial Required)
Pain is a common problem in Medicare End-Stage Renal Disease (ESRD) Hemodialysis (HD) patients, but its prevalence varies widely by geography, dialysis unit, and possibly, ethnicity. Perception of pain has been linked to decreased quality of life, lack of social support, depressed mood and other mental health disorders. Chronic opioid prescription has been identified in approximately 20% of US ESRD HD patients, far higher than the rate in Medicare comparison populations. Opioid doses prescribed to HD patients exceed Centers for Disease Control and Prevention (CDC) recommendations. Prescription and dose level have been asso...
Source: NIDDK Funding Opportunities - December 10, 2018 Category: Endocrinology Source Type: funding
Emotion Regulation, Aging and Mental Disorder (R01 Clinical Trial Not Allowed)
Funding Opportunity PA-19-094 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications for mechanistic research on age-related changes in emotion regulation and how they may contribute to mental disorders in middle-aged and older adults.In particular, research is sought that will advance understanding of irregularities in the integrative neural-behavioral mechanisms of emotion regulation in adult mood and anxiety disorders, and that will examine whether the irregularities are associated with typical or atypical maturational trajectories of emotion processing. If ol...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 29, 2018 Category: Research Source Type: funding
Emotion Regulation, Aging and Mental Disorder (R21 Clinical Trial Not Allowed)
Funding Opportunity PA-19-095 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applications for mechanistic research on age-related changes in emotion regulation and how they may contribute to mental disorders in middle-aged and older adults.In particular, research is sought that will advance understanding of irregularities in the integrative neural-behavioral mechanisms of emotion regulation in adult mood and anxiety disorders, and that will examine whether the irregularities are associated with typical or atypical maturational trajectories of emotion processing. If ol...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 29, 2018 Category: Research Source Type: funding
Youth Mental Health Initiative
Training, technical assistance, and access to funding for community-based organizations to reduce depression, anxiety, and suicide among youth from underserved populations, including culturally diverse, rural, and LGBTQ populations. Geographic coverage: Nationwide -- National Council for Behavioral Health (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - September 19, 2018 Category: American Health Source Type: funding
Role of Gut Microbiome in Regulating Reproduction and Its Impact on Fertility Status in Women Living with and Without HIV (R21 Clinical Trial Optional)
Funding Opportunity PA-18-839 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from the scientific community to support outstanding research related to the role of the gut microbiome in regulating metabolism and reproduction, and its impact on the fertility status. The overarching goal is to gain fundamental insight into the possible role of the gut microbiome in regulating reproduction through HPG, HPA, and HPT axes in the brain. The results of the study could lead to development of diagnostic markers (signature microbiomes) for reprodu...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 26, 2018 Category: Research Source Type: funding
Role of Gut Microbiome in Regulating Reproduction and Its Impact on Fertility Status in Women Living with and Without HIV (R01 - Clinical Trial Optional)
Funding Opportunity PA-18-838 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to encourage applications from the scientific community to support outstanding research related to the role of the gut microbiome in regulating metabolism and reproduction, and its impact on the fertility status. The overarching goal is to gain fundamental insight into the possible role of the gut microbiome in regulating reproduction through HPG, HPA, and HPT axes in the brain. The results of the study could lead to development of diagnostic markers (signature microbiomes) for reprodu...
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 26, 2018 Category: Research Source Type: funding
Two Years (or so) of “Open Mike”
Last year, as I reflected on finishing my first full year as NIH Deputy Director for Extramural Research, I noted five themes that reflected most of the content of this blog: applicant behavior, activity, and outcomes; peer review; basic science; biomedical research workforce and training; and scientific rigor, transparency, and research impact. Looking back on 2017, which was certainly a busy and active year, many of these themes continue to be at the forefront, though one in particular, the make-up and future of the biomedical research workforce, has been the center of much debate.
On May 2, we posted a blog on “Implem...
Source: NIH Extramural Nexus - December 29, 2017 Category: Research Authors: Mike Lauer Tags: blog Open Mike General Source Type: funding
NCCIH Natural Product Phase II Clinical Trial Cooperative Agreement (U01 Clinical Trial Required)
Funding Opportunity PAR-18-125 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites cooperative agreement applications for investigator-initiated clinical trials of natural products to treat clinical symptoms such as those associated with sleep disturbance, pain conditions, or some mental health conditions (e.g., mild to moderate depression, anxiety, and post-traumatic stress), or examine the effects of probiotics and other natural products on gut-microbiome interactions with the brain and/or immune system. All applications submitted under this FOA must be supported by suffici...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 30, 2017 Category: Research Source Type: funding
Research To Address Sleep Disorders in the Context of Medical Rehabilitation (R01 Clinical Trial Optional)
Funding Opportunity PAR-18-212 from the NIH Guide for Grants and Contracts. Patients with many disabilities report problems sleeping, but specific sleep disorders are often not diagnosed. Because sleep affects many physiological and behavioral parameters--depression, anxiety, pain, cancer, cardiovascular changes, immune function-- sleep disorders should be diagnosed and appropriately treated to maximize benefit of rehabilitation. Research is needed on ways to best approach this complexity in the context of medical rehabilitation for a primary, non-sleep disorder. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 21, 2017 Category: Research Source Type: funding
Early Stage Testing of Pharmacologic or Device -based Interventions for the Treatment of Mental Health Disorders (R33- Clinical Trial Required)
Funding Opportunity RFA-MH-18-703 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support the early stage testing of pharmacologic interventions with novel mechanisms of action or device-based interventions, for the treatment of symptoms or domains of altered functions in individuals with mental illness (e.g., schizophrenia, depression, autism, obsessive compulsive disorder, anxiety, bipolar disorder). Early intervention studies are also encouraged where symptoms of a disorder have been identified in subjects (a prodromal phase), prior to full diagnostic crit...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 14, 2017 Category: Research Source Type: funding
Early Stage Testing of Pharmacologic or Device-based Interventions for the Treatment of Mental Disorders (R61/R33-Clinical Trial Required)
Funding Opportunity RFA-MH-18-702 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to support the early stage testing of pharmacologic interventions with novel mechanisms of action, or device-based interventions, for the treatment of symptoms or domains of altered functions in individuals with mental illness (e.g., schizophrenia, depression, autism, obsessive compulsive disorder, anxiety, bipolar disorder). Early intervention studies are also encouraged where symptoms of a disorder have been identified in subjects (a prodromal phase), prior to full diagnostic cri...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 14, 2017 Category: Research Source Type: funding
Prescription Drug Abuse (R21 Clinical Trial Optional)
Funding Opportunity PA-18-076 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applicants to develop innovative research applications on prescription drug abuse, including research to examine the factors contributing to prescription drug abuse; to characterize the adverse medical, mental health and social consequences associated with prescription drug abuse; and to develop effective prevention and service delivery approaches and behavioral and pharmacological treatments. Applications to address these issues are encouraged across a broad range of methodological approache...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 2, 2017 Category: Research Source Type: funding
Prescription Drug Abuse (R01 Clinical Trial Optional)
Funding Opportunity PA-18-058 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) encourages applicants to develop innovative research applications on prescription drug abuse, including research to examine the factors contributing to prescription drug abuse; to characterize the adverse medical, mental health and social consequences associated with prescription drug abuse; and to develop effective prevention and service delivery approaches and behavioral and pharmacological treatments. Applications to address these issues are encouraged across a broad range of methodological approache...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 2, 2017 Category: Research Source Type: funding
NCCIH Natural Product Phase II Clinical Trial Cooperative Agreement (U01)
Funding Opportunity ID: 292366 Opportunity Number: PAR-17-216 Opportunity Title: NCCIH Natural Product Phase II Clinical Trial Cooperative Agreement (U01)Opportunity Category: DiscretionaryOpportunity Category Explanation: Funding Instrument Type: Cooperative AgreementCategory of Funding Activity: HealthCategory Explanation: CFDA Number(s): 93.213Eligible Applicants: State governmentsCounty governmentsCity or township governmentsSpecial district governmentsIndependent school districtsPublic and State controlled institutions of higher educationNative American tribal governments (Federally recognized)Publi...
Source: Grants.gov - March 10, 2017 Category: Research Tags: Health Source Type: funding
NCCIH Natural Product Phase II Clinical Trial Cooperative Agreement (U01)
Funding Opportunity PAR-17-216 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) invites cooperative agreement applications for investigator-initiated clinical trials of natural products to treat clinical symptoms such as those associated with sleep disturbance, pain conditions, or some mental health conditions (e.g., mild to moderate depression, anxiety, and post-traumatic stress), or examine the effects of probiotics and other natural products on gut-microbiome interactions with the brain and/or immune system. All applications submitted under this FOA must be supported by suffici...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 10, 2017 Category: Research Source Type: funding
