Efficacy and safety of Tibetan medicine Qingpeng ointment for acute gouty arthritis: protocol for a multi-center, randomized, double-blind, placebo-controlled trial
This study is designed as a multi-center, randomized, double-blind, placebo-controlled trial. Two hundred and six adults with acute flare of gout, and visual analogue scale (VAS) score of joint pain ≥ 3 points will be recruited. Participants will be randomly assigned to herbal treatment or placebo group at a ratio of 1:1. Qingpeng ointment, or equal placebo ointment, will be applied topically at involved joints twice a day for consecutive 7 days. Patients in both groups would be allowed givin g diclofenac sodium sustained-release tablets as rescue therapy when VAS score of joint pain ≥ 7 points during the treatment. Th...
Source: Trials - May 12, 2022 Category: Research Source Type: clinical trials

Effect of multimodal intervention care on cachexia in patients with advanced cancer compared to conventional management (MIRACLE): an open-label, parallel, randomized, phase 2 trial
In this study, we did not overly restrict the type of cancer or chemotherapy. Therefore, we attempted to measure the effects of complex interventions while preserving clinical situations. Thus, it is expected that the results of this study can be applied effectively to real-world practice.Trial registrationThis clinical trial was registered in the Clinical Research Information Service (KCT0004967), Korean Clinical Trial Registry on April 27, 2020, andClinicalTrial.gov (NCT 04907864) on June 1, 2021. (Source: Trials)
Source: Trials - April 11, 2022 Category: Research Source Type: clinical trials

Stress-induced Sleep Deficits and a Complementary Therapy
Condition:   Insomnia Due to Anxiety and Fear Interventions:   Dietary Supplement: DHM;   Dietary Supplement: Placebo Sponsors:   University of Southern California;   University of California, Los Angeles Active, not recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 15, 2022 Category: Research Source Type: clinical trials