Seeking Your Input on Simplifying Review Criteria
Bruce Reed, Ph.D., Deputy Director of the NIH Center for Scientific Review Guest post by Bruce Reed, Deputy Director of the NIH Center for Scientific Review, originally released on the Review Matters blog Over the past several years we have heard consistent concerns about the complexity of review criteria and administrative load of peer review. CSR shares the concern that the current set of standards has the unintended consequence of dividing reviewer attention among too many questions, thus reducing focus on scientific merit and increasing reviewer burden. Each element was intended make review better, but we w...
Source: NIH Extramural Nexus - February 27, 2020 Category: Research Authors: Bruce Reed Tags: blog Open Mike CSR Peer review Source Type: funding

National Cooperative Drug/Device Discovery/Development Groups (NCDDG) for the Treatment of Mental or Substance Use Disorders or Alcohol Disorder (U01 Clinical Trial Optional)
Funding Opportunity PAR-20-118 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement is to accelerate innovative drug and device therapies translation from discovery to early human studies. Studies responsive to this FOA will develop pharmacologic and neuromodulatory tools for basic and clinical research on mental health disorders, substance use disorders (SUDs) or alcohol addiction; develop and validate tools (pharmacologic or neurostimulation) in support of experimental therapeutic studies of innovative new candidates for mental disorders; and support early-stage human studi...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 25, 2020 Category: Research Source Type: funding

Exploring the Roles of Biomolecular Condensates (BMCs) in HIV replication, latency, or pathogenesis in the context of substance use disorders (R21/R33 Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-21-004 from the NIH Guide for Grants and Contracts. To support research projects exploring the roles of biomolecular condensates (BMCs) and their regulators in processes relevant to HIV/SIV infection, replication, latency, or pathogenesis in the context of substance use disorders. These processes could include studies exploring BMC involvement in HIV infection, HIV replication (including viral gene expression), HIV latency formation or maintenance (including chromatin structure), or HIV pathogenesis (including neurodegenerative processes). Studies could also include investigation of roles for ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - February 24, 2020 Category: Research Source Type: funding

HEAL Initiative: Pain Management Effectiveness Research Network: Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)
Funding Opportunity RFA-NS-20-028 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to solicit cooperative agreement applications that propose clinical trials to test the comparative effectiveness of existing pharmacological therapies or devices for prevention or management of pain while reducing risk of addiction. The studies must evaluate methods to manage specific pain conditions that are within the mission and research interests of participating NIH Institutes and Centers, and evaluate interventions including medications, biologics, medical and assistive devic...
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 21, 2020 Category: Research Source Type: funding

Notice of Special Interest (NOSI): Biomarkers and Biotypes of Drug Addiction
Notice NOT-DA-20-012 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - January 6, 2020 Category: Research Source Type: funding

Addiction Medicine Fellowship Program
Grants to expand the number of fellows at accredited Addiction Medicine Fellowship and Addiction Psychiatry Fellowship programs trained as addiction medicine specialists who work in underserved, community-based settings that integrate primary care with mental health disorders and substance use disorder prevention and treatment services. Geographic coverage: Nationwide -- Health Resources and Services Administration, U.S. Department of Health and Human Services (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - December 4, 2019 Category: American Health Source Type: funding

4DN Organization and Function in Human Health and Disease (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-RM-20-005 from the NIH Guide for Grants and Contracts. To support projects that apply new or existing tools to monitor and/or manipulate the 4D nucleome in the context of human health and disease. Any human disease or biological process relevant to NIHs mission may be proposed including environmental exposures (e.g. addictive substances, toxins, psychosocial stress), or studies across development or lifespan. Other relevant timeframes may include but are not limited to: circadian rhythms, fasting and feeding cycles, reproductive cycles, and sleep/wake cycles. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 25, 2019 Category: Research Source Type: funding

New Investigator Projects on 4DN Organization and Function in Human Health and Disease (U01 Clinical Trial Not Allowed)
Funding Opportunity RFA-RM-20-006 from the NIH Guide for Grants and Contracts. To support projects from NIH-defined New Investigators that apply new or existing tools to monitor and/or manipulate the 4D nucleome (4DN) in the context of human health and disease. Any human disease or biological process relevant to NIHs mission may be proposed including environmental exposures (e.g. addictive substances, toxins, psychosocial stress), or studies across development or lifespan. Other relevant time frames may include but are not limited to: circadian rhythms, fasting and feeding cycles, reproductive cycles, and sleep/wake cyc...
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 25, 2019 Category: Research Source Type: funding

Assessing the Effects of Cannabinoids on HIV-Induced Inflammation (R01 Clinical Trial Optional)
Funding Opportunity RFA-DA-20-022 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement [FOA] is to encourage basic science and preclinical research to determine the biological mechanisms underlying the effects of cannabinoids and the endocannabinoid system on HIV-associated persistent inflammation and its consequent effects on nervous system function. Projects submitted in response to this FOA must include expertise and resources in both areas of HIV/AIDS and addiction science. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - November 7, 2019 Category: Research Source Type: funding

Integrative Research on Polysubstance Abuse and Disorder (R61/R33 Clinical Trial Optional)
Funding Opportunity PAR-20-035 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is supported by Collaborative Research on Addiction (CRAN) at the National Institutes of Health (NIH), a trans-NIH partnership composed of the National Institute on Alcohol Abuse and Alcoholism (NIAAA), the National Institute on Drug Abuse (NIDA), and the National Cancer Institute (NCI). The intent of this FOA is two-fold: (1) characterize how the neurobiological alterations, associated behaviors, and public health consequences arising from polysubstance use differ from, or are similar to, those observ...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 18, 2019 Category: Research Source Type: funding

HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 - Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-20-011 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) aims to speed scientific solutions to stem the national opioid public health crisis by supporting the development of therapies and technologies directed at enhanced pain management through the Small Business Innovation Research (SBIR) program. This FOA is focused on applications directed at improving pain treatment, including the development of new non-addictive medications and devices and objective pain measurement. In addition, NIH is interested in new screening tools and models foc...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 4, 2019 Category: Research Source Type: funding

HEAL INITIATIVE: Development of Therapies and Technologies Directed at Enhanced Pain Management (R43/R44 - Clinical Trial Required)
Funding Opportunity RFA-NS-20-010 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) aims to speed scientific solutions to stem the national opioid public health crisis by supporting the development of therapies and technologies directed at enhanced pain management through the Small Business Innovation Research (SBIR) program. This FOA is focused on applications directed at improving pain treatment, including the development of new non-addictive medications and devices and objective pain measurement. In addition, NIH is interested in new screening tools and models foc...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 4, 2019 Category: Research Source Type: funding

HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Required)
Funding Opportunity RFA-NS-20-008 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) aims to speed scientific solutions to stem the national opioid public health crisis by supporting the development of therapies and technologies directed at enhanced pain management through the Small Business Technology Transfer (STTR) program. This FOA is focused on applications directed at improving pain treatment, including the development of new non-addictive medications and devices and objective pain measurement. In addition, NIH is interested in new screening tools and models foc...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 4, 2019 Category: Research Source Type: funding

HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-20-009 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) aims to speed scientific solutions to stem the national opioid public health crisis by supporting the development of therapies and technologies directed at enhanced pain management through the Small Business Technology Transfer (STTR) program. This FOA is focused on applications directed at improving pain treatment, including the development of new non-addictive medications and devices and objective pain measurement. In addition, NIH is interested in new screening tools and models foc...
Source: NIH Funding Opportunities (Notices, PA, RFA) - October 4, 2019 Category: Research Source Type: funding

HEAL Initiative: Development of Therapies and Technologies Directed at Enhanced Pain Management (R41/R42 Clinical Trial Not Allowed)
The purpose of this Funding Opportunity Announcement (FOA) aims to speed scientific solutions to stem the national opioid public health crisis by supporting the development of therapies and technologies directed at enhanced pain management through the Small Business Technology Transfer (STTR) program. This FOA is focused on applications directed at improving pain treatment, including the development of new non-addictive medications and devices and objective pain measurement. In addition, NIH is interested in new screening tools and models focused specifically on pain and development of pain therapies.RFA-NS-20-009 (Source:...
Source: NIDDK Funding Opportunities - October 4, 2019 Category: Endocrinology Source Type: funding