HEAL Initiative: Pain Management Effectiveness Research Network: Clinical Trial Planning and Implementation Cooperative Agreement (UG3/UH3 Clinical Trial Required)

Funding Opportunity RFA-NS-20-028 from the NIH Guide for Grants and Contracts. The purpose of this Funding Opportunity Announcement (FOA) is to solicit cooperative agreement applications that propose clinical trials to test the comparative effectiveness of existing pharmacological therapies or devices for prevention or management of pain while reducing risk of addiction. The studies must evaluate methods to manage specific pain conditions that are within the mission and research interests of participating NIH Institutes and Centers, and evaluate interventions including medications, biologics, medical and assistive devices or delivery system strategies in controlled trials. This FOA does not include testing behavioral interventions for management of pain. The overall goal is to inform clinicians about the effectiveness of pharmacological or device interventions or management strategies concerning use of these interventions that reduce opioid use, improve functional outcomes and reduce pain for diseases or conditions of interest. Clinical trials will be conducted within the infrastructure of the HEAL Pain Effectiveness Research Network.
Source: NIH Funding Opportunities (Notices, PA, RFA) - Category: Research Source Type: funding

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Source: Frontiers in Pharmacology - Category: Drugs & Pharmacology Source Type: research
Abstract Pain is an unpleasant sensory and emotional experience in many diseases and is often caused by intense or damaging stimuli. Pain negatively affects the quality of life and increases high health expenditures. Drugs with analgesic properties are commonly used to relieve pain, but these Western medications could be overwhelmed by side effects including tolerance and addiction. Herbal medicines may provide alternative measures for pain management. In this review paper, after introduction of Chinese medicine theory and treatment modality, emphasis is placed on the application of Chinese herbs and herbal formul...
Source: The American Journal of Chinese Medicine - Category: Complementary Medicine Authors: Tags: Am J Chin Med Source Type: research
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Source: Dental Technology Blog - Category: Dentistry Source Type: news
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Source: The Clinical Journal of Pain - Category: Anesthesiology Tags: Review Article Source Type: research
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Source: Harvard Health Blog - Category: Consumer Health News Authors: Tags: Complementary and alternative medicine Mind body medicine Pain Management Source Type: blogs
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Source: Instructional Course Lectures - Category: Orthopaedics Tags: Instr Course Lect Source Type: research
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Source: Pain and Therapy - Category: Anesthesiology Source Type: research
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Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research
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Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research
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