HEAL Initiative: Career Development Awards in Implementation Science for Substance Use Prevention and Treatment (K23 - Clinical Trial Required)
Funding Opportunity PAS-22-207 from the NIH Guide for Grants and Contracts. This HEAL FOA provides an opportunity for early career researchers or early career clinicians with foundational backgrounds in addiction to develop expertise in implementation science. Successful applicants would propose training in implementation science methods, and a research project that would apply these to at least one of the four priority domains of the HHS Overdose Prevention Strategy: primary prevention (including appropriate opioid prescribing), OUD treatment, harm reduction, and/or recovery support services. The overarching goal is to...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 14, 2022 Category: Research Source Type: funding

HEAL Initiative: Preventing Opioid Misuse and Co-Occurring Conditions by Intervening on Social Determinants (R01 - Clinical Trials Optional)
Funding Opportunity RFA-DA-23-051 from the NIH Guide for Grants and Contracts. In April 2018, the National Institutes of Health (NIH) launched the Helping to End Addiction Long-term Initiative or HEAL Initiative, an aggressive, trans-agency effort to speed scientific solutions to stem the national opioid public health crisis. Through this initiative, the National Institute on Drug Abuse, in partnership with other NIH Institutes, Centers, and Offices, requests applications for studies designed to develop and test interventions to prevent opioid misuse, opioid use disorder, and co-occurring conditionsby intervening on soc...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 13, 2022 Category: Research Source Type: funding

HEAL Initiative Notice of Special Interest (NOSI): Development and Validation of Pain-Related Models and Endpoints to Facilitate Non-Addictive Analgesic Discovery
Notice NOT-NS-22-095 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 13, 2022 Category: Research Source Type: funding

HEAL Initiative: Rapidly Assessing the Public Health Impact of Emerging Opioid Threats (UG1 - Clinical Trial Optional)
Funding Opportunity RFA-DA-23-045 from the NIH Guide for Grants and Contracts. The need to rapidly develop methods to assess the prevalence / health impact of emerging illicit drugs has never been greater. Illicit chemists are marketing potent drugs of abuse taken from deep wells of scientific and patent literature, which we can expect to continue to yield new drugs for many years. Over the last few years, fentanyl/fentalogs (fentanyl-related opioids) have flooded the illicit opioid market, which has complicated patient stabilization / harm reduction, and caused mortality rates to skyrocket. Even understanding the drugs...
Source: NIH Funding Opportunities (Notices, PA, RFA) - July 7, 2022 Category: Research Source Type: funding

Clinical and Translational Scholarship Program
The opportunity for 2 days of in-person comprehensive training and consultation with clinicians, faculty, and staff experts from the University of Vermont Center on Rural Addiction. The program is intended for teams of up to 4 individuals from practices in rural counties in Vermont, New Hampshire, Maine, and New York. Geographic coverage: Maine, New Hampshire, New York, Vermont -- University of Vermont Center on Rural Addiction (Source: Funding opportunities via the Rural Health Information Hub)
Source: Funding opportunities via the Rural Health Information Hub - July 1, 2022 Category: American Health Source Type: funding

Introducing Ericka Boone, the New Director of the Biomedical Research Workforce Division
Dr. Ericka Boone, Director, Division of Biomedical Research Workforce I am pleased to announce the appointment of Dr. Ericka Boone as the new director of the Division of Biomedical Research Workforce (DBRW) in the NIH Office of Extramural Research (OER), and I am thrilled she agreed to take on this role, given her background, interest, passions, and work ethic. I am very optimistic that DBRW is in great hands. Through her efforts and in close coordination with other components across NIH and beyond, I anticipate her appointment will lead to substantive advancements in the wellbeing of the NIH funded extramural research wor...
Source: NIH Extramural Nexus - June 30, 2022 Category: Research Authors: Mike Lauer Tags: blog Open Mike Biomedical Workforce NGRI scientific workforce diversity UNITE Source Type: funding

Transformative Research on the Basic Mechanisms of Polysubstance use in Addiction (R01 - Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-23-015 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) will support projects proposing mechanistic studies that will transform our understanding of polysubstance use in addiction. These hypothesis-based, exploratory projects may investigate mechanisms of polysubstance use at the behavioral, cognitive, cellular, circuit, genetic, epigenetic, pharmacological and/or computational levels. (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - June 2, 2022 Category: Research Source Type: funding

Behavioral and Integrative Treatment Development Program (R01 Clinical Trial Optional)
Funding Opportunity PAR-22-182 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to encourage behavioral intervention development research to test efficacy, conduct clinical trials, examine mechanisms of behavior change, determine dose-response, treatment optimization, and/or ascertain best sequencing of behavioral, combined, sequential, or integrated behavioral and pharmacological (1) drug abuse treatment interventions, including interventions for patients with comorbidities; (2) drug abuse treatment and adherence interventions; (3) drug abuse treatment and adher...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 9, 2022 Category: Research Source Type: funding

Behavioral and Integrative Treatment Development Program (R34 Clinical Trial Optional)
Funding Opportunity PAR-22-183 from the NIH Guide for Grants and Contracts. The purpose of this funding opportunity announcement (FOA) is to encourage behavioral intervention development research to test efficacy, conduct clinical trials, examine mechanisms of behavior change, determine dose-response, treatment optimization, and/or ascertain best sequencing of behavioral, combined, sequential, or integrated behavioral and pharmacological (1) drug abuse treatment interventions, including interventions for patients with comorbidities; (2) drug abuse treatment and adherence interventions; (3) drug abuse treatment and adher...
Source: NIH Funding Opportunities (Notices, PA, RFA) - May 9, 2022 Category: Research Source Type: funding

Pathogenic Mechanisms influencing Blood Brain Barrier function in HIV and Substance Use Disorders (R01 Clinical Trial Optional)
Funding Opportunity RFA-DA-23-012 from the NIH Guide for Grants and Contracts. The blood brain barrier (BBB) is a target of both the HIV virus and substances of abuse. It is a site of entry for HIV infected monocytes and macrophages that can traverse the BBB either paracellularly or transcellularly. HIV viral proteins can also attack astrocytes and tight junctions of BBB directly and compromise its integrity, resulting in the crossing of the virus, as well as abused substances, into the brain. Meanwhile, many substances of abuse cause BBB dysfunction. Because BBB integrity regulates both substances and virus levels in t...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 26, 2022 Category: Research Source Type: funding

Notice of Early Termination of RFA-NS-21-015 "HEAL Initiative: Team Research for Initial Translational Efforts in Non-addictive Analgesic Therapeutics Development (U19 Clinical Trial Not Allowed)
Notice NOT-NS-22-049 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 22, 2022 Category: Research Source Type: funding

HEAL Initiative: Team Research for Initial Translational Efforts in Non-addictive Analgesic Therapeutics Development [Small Molecules and Biologics] (U19 Clinical Trial Not Allowed)
Funding Opportunity RFA-NS-22-052 from the NIH Guide for Grants and Contracts. This funding opportunity announcement (FOA) is part of a suite of FOAs to support the development of safe, effective, and non-addictive therapeutics to treat pain. The goal of this FOA is to support team-based research projects to develop assays, screening and early optimization work to develop a non-addictive therapeutic to treat pain. Discovery and validation of pharmacodynamic markers efficacy and pharmacokinetic/pharmacodynamic (PK/PD) studies are also responsive. The result of the project should be to advance a hit or lead to the point w...
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 22, 2022 Category: Research Source Type: funding

Notice of Special Interest (NOSI): Availability of Administrative Supplements for Helping to End Addiction Long-term (HEAL) Initiative awardees to make data Findable, Accessible, Interoperable, and Reusable (FAIR) through the HEAL Data Ecosystem
Notice NOT-OD-22-110 from the NIH Guide for Grants and Contracts (Source: NIH Funding Opportunities (Notices, PA, RFA))
Source: NIH Funding Opportunities (Notices, PA, RFA) - April 22, 2022 Category: Research Source Type: funding

NIDA Research Center of Excellence Grant Program (P50 Clinical Trial Optional)
Funding Opportunity PAR-22-133 from the NIH Guide for Grants and Contracts. This Funding Opportunity Announcement (FOA) is to provide support for research Centers that (1) conduct drug abuse and addiction research in any area of NIDAs mission, (2) have outstanding innovative science, (3) are multidisciplinary, thematically integrated, synergistic, and (4) serve as national resource(s) to provide educational and outreach activities to drug abuse research communities, educational organizations, the general public, and policy makers in the NIDA research fields. It is expected that a Center will transform knowledge in the s...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 14, 2022 Category: Research Source Type: funding

Enhancing Social Connectedness and Ameliorating Loneliness to Prevent and Treat SUD and Support Recovery (R21 - Clinical Trial Not Allowed)
Funding Opportunity RFA-DA-23-009 from the NIH Guide for Grants and Contracts. oThis initiative will fund exploratory or pilot research projects to test interventions that address social connectedness and/or loneliness in order to prevent or treat SUDs or enhance recovery for individuals with SUDs. Interventions funded through this initiative should build on foundational, epidemiologic research on social connectedness and loneliness, and help contribute to a more unified theory about the role of loneliness and social connectedness in substance use and SUDs. Interventions could be delivered at the individual, dyadic, fam...
Source: NIH Funding Opportunities (Notices, PA, RFA) - March 14, 2022 Category: Research Source Type: funding