Dual thrombolytic therapy with mutant pro-urokinase and small bolus alteplase for ischemic stroke (DUMAS): study protocol for a multicenter randomized controlled phase II trial
DiscussionWhen dual thrombolytic therapy with a small bolus alteplase and m-proUK shows the anticipated effect on the outcome, this will lead to a 13% absolute reduction in the occurrence of ICH in patients with ischemic stroke.Trial registrationNL7409 (November 26, 2018)/NCT04256473 (February 5, 2020) (Source: Trials)
Source: Trials - August 9, 2022 Category: Research Source Type: clinical trials

EXtending the Time Window for Thrombolysis in Posterior Circulation Stroke Without Early CT Signs
Condition:   Stroke, Acute Ischemic Intervention:   Drug: Tissue Plasminogen Activator (Alteplase) Sponsor:   Second Affiliated Hospital, School of Medicine, Zhejiang University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - June 23, 2022 Category: Research Source Type: clinical trials