Viscoelastic Testing Guided Tissue Plasminogen Activator Treatment in Acute Respiratory Failure
Conditions: Acute Respiratory Failure; Hypercoagulability; Fibrinolysis Shutdown Intervention: Drug: Alteplase Sponsor: South West Sydney Local Health District Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 15, 2022 Category: Research Source Type: clinical trials
Control of Line Complications with KiteLock (CLiCK) in the critical care unit: study protocol for a multi-center, cluster-randomized, double-blinded, crossover trial investigating the effect of a novel locking fluid on central line complications in the critical care population
DiscussionIf successful, the results of this study can serve as evidence for a shift of standard of care practices to include EDTA locking fluid in routine CVAD locking procedures. Completion of this study has the potential to improve CVAD standard of care to become safer for patients, as well as provides an opportunity to decrease strain on healthcare budgets related to treating preventable CVAD complications. Success and subsequent implementation of this intervention in the ICU may also be extrapolated to other patient populations with heavy CVAD use including hemodialysis, oncology, parenteral nutrition, and pediatric p...
Source: Trials - August 30, 2022 Category: Research Source Type: clinical trials
Reduced Dose Thrombolytic in Intermediate/High Risk Pulmonary Thromboembolism
Condition: Pulmonary Embolism Interventions: Drug: Tissue Plasminogen Activator, Alteplase; Drug: Low-molecular weight heparin Sponsor: Ege University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - August 23, 2022 Category: Research Source Type: clinical trials
