FASCE, the benefit of spironolactone for treating acne in women: study protocol for a randomized double-blind trial
DiscussionThe treatment frequently used in female acne is systemic antibiotics with many courses, as it is a chronic inflammatory disease. In the context of the recent World Health Organisation (WHO) revelation about the serious, worldwide threat to public health of antibiotic resistance, this trial could give the physician another alternative in the treatment of adult female acne instead of using isotretinoin, which is more complex to manage.Trial registrationClinicalTrials.gov:NCT03334682. Registered on 7 November 2017. (Source: Trials)
Source: Trials - June 24, 2020 Category: Research Source Type: clinical trials
Combination With Inhibitor of Neutrophil Elastase (All-trans Retinoic Acid ) and Isotretinoin May Enhances Neutralizing Antibodies in COVID -19 Infected Patients Better Than COVID-19 Inactivated Vaccines
Condition: COVID -19 Interventions: Drug: Aerosolized 13 cis retinoic acid; Drug: Aerosolized All trans retinoic acid; Other: Placebo Sponsors: Kafrelsheikh University; Damietta University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 20, 2020 Category: Research Source Type: clinical trials
Combination With Alvelestat and Isotretinoin May Enhances Neutralizing Antibodies in COVID -19 Infected Patients Better Than COVID-19 Inactivated Vaccines
Condition: COVID -19 Interventions: Drug: Alvelestat (MPH996) Plus Aerosolized 13 cis retinoic acid; Other: Placebo Sponsors: Kafrelsheikh University; Damietta University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 20, 2020 Category: Research Source Type: clinical trials
Combination With Inhibitor of Neutrophil Elastase (All-trans Retinoic Acid ) and Isotretinoin May Enhances Neutralizing Antibodies in COVID -19 Infected Patients Better Than COVID-19 Inactivated Vaccines
Condition: COVID -19 Interventions: Drug: Aerosolized 13 cis retinoic acid; Drug: Aerosolized All trans retinoic acid; Other: Placebo Sponsors: Kafrelsheikh University; Damietta University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 20, 2020 Category: Research Source Type: clinical trials
Combination With Alvelestat and Isotretinoin May Enhances Neutralizing Antibodies in COVID -19 Infected Patients Better Than COVID-19 Inactivated Vaccines
Condition: COVID -19 Interventions: Drug: Alvelestat (MPH996) Plus Aerosolized 13 cis retinoic acid; Other: Placebo Sponsors: Kafrelsheikh University; Damietta University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 20, 2020 Category: Research Source Type: clinical trials
Combination With Inhibitor of Neutrophil Elastase (All-trans Retinoic Acid ) and Isotretinoin May Enhances Neutralizing Antibodies in COVID -19 Infected Patients Better Than COVID-19 Inactivated Vaccines
Condition: COVID -19 Interventions: Drug: Aerosolized 13 cis retinoic acid; Drug: Aerosolized All trans retinoic acid; Other: Placebo Sponsors: Kafrelsheikh University; Damietta University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 20, 2020 Category: Research Source Type: clinical trials
Combination Therapy With Isotretinoin and Tamoxifen May Provide Complete Protection Against Severe Acute Respiratory Syndrome Coronavirus
Condition: COVID-19 Interventions: Drug: Drug: Isotretinoin plus Tamoxifen; Drug: Aerosolized Isotretinoin plus Tamoxifen Sponsor: Kafrelsheikh University Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - May 15, 2020 Category: Research Source Type: clinical trials
