Impaired dynamic interaction of axonal endoplasmic reticulum and ribosomes contributes to defective stimulus –response in spinal muscular atrophy

ConclusionsThese findings implicate impaired dynamic interplay between the ribosomes and ER in axon terminals of motoneurons as a contributor to the pathophysiology of SMA and possibly also other motoneuron diseases.
Source: Translational Neurodegeneration - Category: Neurology Source Type: research