Misleading clinical evidence and systematic reviews on ivermectin for COVID-19

Since WHO declared the COVID-19 as a pandemic,1 2 healthcare systems all over the world have focused their efforts on limiting the spread of SARS-CoV-2, and despite the ceaseless development of strategies to struggle with the impact of COVID-19, there is no sign of let-up. And the stress and overburden elicited by the pandemic—especially in vulnerable or marginalised populations—remain unstoppable, while the possibility of massive vaccination gives hope for a respite.3 4 Beyond public health interventions, several drugs have been considered for the treatment of SARS-CoV-2 infection,5 which triggers severe respiratory symptoms and critical illness in approximately 5%–20% of patients, with intensive care requirements and high mortality.6–10 In this article, we appraise and debate about the available evidence regarding the role of ivermectin for COVID-19. Randomised Evaluation of COVID-19...
Source: Evidence-Based Medicine - Category: Internal Medicine Authors: Tags: COVID-19 EBM opinion and debate Source Type: research