Reduction of residual topical diclofenac in waste water by a wiping procedure before hand washing

Diclofenac is non-steroidal anti-inflammatory drug (NSAID) with widespread usage as a topical treatment for relief of pain and inflammation in soft-tissue injuries. While the permeation mechanisms of topically applied diclofenac are well documented, the fate of residual diclofenac not retained at the site of pain following subsequent hand-washing is still not well characterized. The aim of this study quantifies the amount of diclofenac present in rinse water after the application of a topical pain gel containing 23.2 mg/g diclofenac diethylamine, and subsequent washing of the hands. A comparison of two different hand washing techniques was completed with and without wiping hands directly after product application and before washing.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news