α-2,6-sialic acid/IgG anti-dsDNA ratios correlate with human lupus disease activity and possible mechanisms: A pilot study

CONCLUSION: α2,6-SIA/IgG anti-dsDNA ratios inversely forecasted SLEDAI scores. Possible mechanisms may be due to the different effects of sialylated and deSIA IgG anti-dsDNA on lupus B cells in terms of IL-10 secretion and SIA/IgG anti-dsDNA ratios.PMID:35531921 | DOI:10.1177/09612033221099766

Source: Lupus - May 9, 2022 Category: Rheumatology Authors: Lieh-Bang Liou Ting-Yi Wang I-Ju Liu Han-Chung Wu Po-Yuan Ke Yao-Fan Fang Yen-Fu Chen Source Type: research