Po-713-05 ischemic stroke after prophylaxis with left atrial appendage closure vs non-warfarin oral anticoagulants: a “real-world” multicenter comparison of stroke severity

In randomized trials, strokes occurring in patients who have received left atrial appendage closure (LAAC) devices have been less severe than in patients receiving warfarin prophylaxis - an observation thought related to warfarin ’s higher rate of hemorrhagic stroke (which are known to have worse outcomes). Similar stroke rates have been described with LAAC vs NOACs (non-warfarin oral anticoagulants), but the low hemorrhagic stroke rate of NOACs raises the question of stroke severity between these two therapies.

Source: Heart Rhythm - April 29, 2022 Category: Cardiology Authors: Mohit K. Turagam, Iwanari Kawamura, Domenico G. Della Rocca, Pavel Hala, Thomas Flautt, Deji Adedokun, Moritoshi Funasako, Daniel Ross Musikantow, Srinivas R. Dukkipati, David H. Yoo, Petr Neuzil, Devi G. Nair, Douglas N. Gibson, Miguel Valderrabano, Andr Source Type: research