Meta-Analysis of Percutaneous Coronary Intervention Versus Coronary Artery Bypass Grafting for Left Main Narrowing

Randomized controlled trials (RCTs) comparing percutaneous coronary intervention (PCI) with drug-eluting stents and coronary artery bypass grafting (CABG) for patients with left main coronary artery disease (LMCAD) have reported conflicting results. We performed a systematic review up to May 23, 2021, and 1-stage reconstructed individual patient data meta-analysis (IPDMA) to compare outcomes between both groups. The primary outcome was 10-year all-cause mortality. Secondary outcomes included myocardial infarction (MI), stroke, and unplanned revascularization at 5  years.

Source: The American Journal of Cardiology - April 4, 2022 Category: Cardiology Authors: Nicholas W.S. Chew, Chen-Han Ng, Gwyneth Kong, Keng-Siang Lee, Darren J.H. Tan, Oliver Zi-Hern Lim, Yip Han Chin, Bee Choo Tai, Tianyuan Gu, Seung-Jung Park, Duk-Woo Park, Marie-Claude Morice, Theodoros Kofidis, James W.L. Yip, Poay-Huan Loh, Koo-Hui Chan Source Type: research