Updated Criteria to Include Contact Allergens in the European Baseline Series With Suggested Additions

This article discusses these shifts in exposure and hence potential additions and deletions from the EBS.Recent findingsThe formaldehyde-releasing preservatives imidazolidinyl urea 2% pet., diazolidinyl urea 2% pet. and 2-bromo-2-nitropropane-1,3-diol 0.5% pet. should be considered for inclusion in the EBS as published data has shown formaldehyde 2% aq. is an inadequate screen for contact allergy to the formaldehyde releasers. Other potential additions include isothiazolinones preservatives, sodium metabiosulphite, linalool hydroperoxide and limonene hydroperoxide, Compositae mix II, sorbitan monooleate and sorbitan sesquioleate, and the emulsifiers decyl glucoside and lauryl glucoside. Potential deletions include paraben mix and methyldibromogluterile nitrile (MDBGN).SummaryDermatologists who investigate patients for potential ACD have an important role to play in monitoring trends in contact allergy including cosmetovigilance by thoroughly investigating patients and in the subsequent detection and reporting of emerging allergens. Further reports on newly identified allergens create a body of evidence to indicate whether the allergens need to be included in a series of commercially available test allergens. We have discussed a number of emerging allergens which have achieved sufficient evidence to merit their inclusion in the EBS.
Source: Current Treatment Options in Allergy - Category: Allergy & Immunology Source Type: research