The absence of the autoimmune regulator gene (AIRE) impairs the three-dimensional structure of medullary thymic epithelial cell spheroids

Besides controlling the expression of peripheral tissue antigens, the autoimmune regulator (AIRE) gene also regulates the expression of adhesion genes in medullary thymic epithelial cells (mTECs), an essential pr...

Source: BMC Cell Biology - March 24, 2022 Category: Cytology Authors: Ana Carolina Monteleone-Cassiano, Janaina A. Dernowsek, Romario S. Mascarenhas, Amanda Freire Assis, Dimitrius Pitol, Natalia Chermont Santos Moreira, Elza Tiemi Sakamoto-Hojo, Jo ão Paulo Mardegan Issa, Eduardo A. Donadi and Geraldo Aleixo Passos Tags: Research Source Type: research