Retrospective Evaluation of Intrapleural Tissue Plasminogen Activator With or Without Dornase Alfa for the Treatment of Traumatic Retained Hemothorax: A 6-Year Experience

CONCLUSIONS AND RELEVANCE: Dornase alfa added to tPA may not reduce the need for operation to treat retained hemothorax. Further studies should be directed at optimal tPA dose determination and economic impact of inappropriate DNase use.PMID:35184602 | DOI:10.1177/10600280221077383

Source: The Annals of Pharmacotherapy - February 21, 2022 Category: Drugs & Pharmacology Authors: Christopher Francis Janowak Bradley Robert Becker Carolyn Dosen Philpott Amy Teres Makley Eric William Mueller Christopher Allen Droege Molly Elizabeth Droege Source Type: research