Neurofilament Light Chain Levels in Multiple Sclerosis Correlate With Lesions Containing Foamy Macrophages and With Acute Axonal Damage

Discussion Our results demonstrated that active and mixed white matter MS lesions with foamy microglia show high acute axonal damage and correlate with elevated CSF NfL levels. Our data support the use of this biomarker to monitor inflammatory demyelinating lesion activity with axonal damage in MS.

http://nn.neurology.org/cgi/content/short/9/3/e1154?rss=1

Source: Neurology Neuroimmunology and Neuroinflammation - March 3, 2022 Category: Neurology Authors: van den Bosch, A., Fransen, N., Mason, M., Rozemuller, A. J., Teunissen, C., Smolders, J., Huitinga, I. Tags: Multiple sclerosis Research Article Source Type: research

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