Serum/glucocorticoid ‐regulated kinase 1‐targeted transient receptor potential oxalate subtype 1 regulates bladder smooth muscle cell proliferation due to bladder outlet obstruction in mice via activated T cell nuclear factor transcription factor 2
In this study, SGK1 targeted TRPV1 to regulate the proliferation of MBSMCs mediated by BOO in mice through NFAT2 and then affected the process of b ladder remodeling after BOO. This finding may provide a strategy for BOO drug target screening.
Source: IUBMB Life - Category: Research Authors: Jiangshu He,
Jin Yang,
Lin Chen,
Pinglin He,
Xun Liu,
Kai Wang,
Taotao Dong,
Jia Li,
Xudong Ma,
Amend Bastian,
Stenzl Arnulf Tags: RESEARCH COMMUNICATION Source Type: research