Ultrafast photooxidation of protein-bound anionic flavin radicals [Chemistry]

The photophysical properties of anionic semireduced flavin radicals are largely unknown despite their importance in numerous biochemical reactions. Here, we studied the photoproducts of these intrinsically unstable species in five different flavoprotein oxidases where they can be stabilized, including the well-characterized glucose oxidase. Using ultrafast absorption and fluorescence spectroscopy, we...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Biophysics and Computational Biology, Chemistry Biological Sciences Source Type: research