Evaluation of hTERT gene expression and chromosome 7 copy number variation in anal squamous intra-epithelial lesions: A pilot study

Conclusions: Positive association of hTERT gene with a-SIL suggests its possible role in evolution of anal squamous abnormalities. Increase in chromosome 7 also correlated positively with a-SIL. These findings corroborate the similarities between squamous carcinogenesis in CIN and a-SIL.

https://www.jcytol.org/text.asp?2022/39/1/14/336177

Source: Journal of Cytology - February 17, 2022 Category: Cytology Authors: Tanvi Arora Neelam Wadhwa Divya Aggarwal Deepika Pandhi Preeti Diwaker Vinod K Arora Source Type: research