Superantigens promote Staphylococcus aureus bloodstream infection by eliciting pathogenic interferon-gamma production [Microbiology]

Staphylococcus aureus is a foremost bacterial pathogen responsible for a vast array of human diseases. Staphylococcal superantigens (SAgs) constitute a family of exotoxins from S. aureus that bind directly to major histocompatibility complex (MHC) class II and T cell receptors to drive extensive T cell activation and cytokine release. Although...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Microbiology Biological Sciences Source Type: research