Bivalent recognition of fatty acyl-CoA by a human integral membrane palmitoyltransferase [Biophysics and Computational Biology]

S-acylation, also known as palmitoylation, is the most abundant form of protein lipidation in humans. This reversible posttranslational modification, which targets thousands of proteins, is catalyzed by 23 members of the DHHC family of integral membrane enzymes. DHHC enzymes use fatty acyl-CoA as the ubiquitous fatty acyl donor and become...
Source: Proceedings of the National Academy of Sciences - Category: Science Authors: Tags: Biochemistry Biological Sciences Source Type: research