Substrate-dependent inhibition of hypericin on human carboxylesterase 2: implications for herb-drug combination

CONCLUSION: These findings are of considerable clinical significance to the combination of hypericin-containing herbs and drugs metabolized by hCE2.PMID:35114918 | DOI:10.2174/1389200223666220202093303

Source: Current Drug Metabolism - February 4, 2022 Category: Drugs & Pharmacology Authors: Dalong Wang Tingting Zhao Shan Zhao Jing Chen Tongyi Dou Guangbo Ge Changyuan Wang Huijun Sun Kexin Liu Qiang Meng Jingjing Wu Source Type: research