Islet amyloid polypeptide cross-seeds tau and drives the neurofibrillary pathology in Alzheimer ’s disease

The pathologic accumulation and aggregation of tau is a hallmark of tauopathies including Alzheimer ’s disease (AD). However, the molecular mechanisms mediating tau aggregation in AD remain elusive. The inciden...

Source: Molecular Neurodegeneration - January 29, 2022 Category: Neurology Authors: Guoxin Zhang, Lanxia Meng, Zhihao Wang, Qinyu Peng, Guiqin Chen, Jing Xiong and Zhentao Zhang Tags: Research article Source Type: research