Exosome-mediated delivery of SCD-1 siRNA promoted the death of anaplastic thyroid carcinoma cells via regulating ROS level

ConclusionsExosomes loaded SCD-1 siRNA inhibited ATC cellular proliferation and promoted cellular apoptosis, and the mechanisms involved maybe the regulation of fatty acids metabolism and ROS level. Our study provides a promising therapeutic strategy for ATC.

http://link.springer.com/10.1007/s12094-021-02682-x

Source: Clinical and Translational Oncology - January 30, 2022 Category: Cancer & Oncology Source Type: research