Factors Affecting Clinical Outcomes of Carbapenem-Resistant Enterobacteriaceae and Carbapenem-Susceptible Enterobacteriaceae Infections

This study aimed to identify risk factors associated with the mortality and readmission of CRE- and carbapenem-susceptible Enterobacteriaceae (CSE)–infected patients in Thailand. Length of stay (LOS) and the cost of treatment for the infections were also investigated. Method A retrospective cohort study was conducted in patients with CRE- and CSE-positive cultures from January 2016 to June 2019 in an advanced-level government hospital in Thailand. Risk factors for mortality and readmission were analyzed by logistic regression analysis. The differences in LOS and cost of treatment between CRE- and CSE-infected patients were analyzed by the independent t test. Results A total of 316 and 329 of the patients that were CRE and CSE culture positive, respectively, were included. Carbapenem-resistant Enterobacteriaceae was significantly associated with 30-day mortality [adjusted odds ratio (aOR), 2.86; 95% confidence interval (CI), 1.84–4.44; P
Source: Infectious Diseases in Clinical Practice - Category: Infectious Diseases Tags: Original Articles Source Type: research