NLRP3 Inflammasome Activation is a Prognostic Marker of Recovery in HEV-Infected Patients

This study highlighted the significance of upregulated NLRP3 inflammasome leading to increased production of IL-18 and IL-1β cytokines in sera of AVH patients. Thus, it indicated the role of Th1 response acting through the NLRP3 pathway which might have been helpful in the recovery of AVH patients. These promising results open multiple treatment avenues where specific inhibitors can be designed to modulate the progress of disease and its pathogenicity.PMID:34982235 | DOI:10.1007/s00284-021-02736-x
Source: Current Microbiology - Category: Microbiology Authors: Source Type: research