A preliminary study on urinary excretion patterns of methylprednisolone after oral and intra-articular administration and effect on endogenous glucocorticosteroids profile
CONCLUSION: The findings reveal that the MP can exceed the reporting level in urine even after administration by permitted route (i.a.). Further analysis of four endogenous GCs (Cortisol, Cortisone, TH Cortisone, and 11-deoxycortisol) showed a decreased excretion following administration of MP by oral & intra-articular routes.
Source: Indian Journal of Pharmacology - Category: Drugs & Pharmacology Authors: Awanish Kumar Upadhyay Sachin Dubey Shobha Ahi Alka Beotra Akhilesh Bhardwaj Sangeeta Shukla Shila Jain Source Type: research