Dynamic Stabilization of Unit Polyion Complexes Incorporating Small Interfering RNA by Fine-Tuning of Cationic Block Length in Two-Branched Poly(ethylene glycol)- < em > b < /em > -poly(l-lysine)

This study revealed that the uPIC formation between siRNA and bPEG-PLys can be controlled by their charges, which may be helpful for designing PIC-based delivery systems.PMID:34935361 | DOI:10.1021/acs.biomac.1c01344

Source: Biomacromolecules - December 22, 2021 Category: Biochemistry Authors: Hiroyuki Chaya Mitsuru Naito Masaru Cho Kazuko Toh Kotaro Hayashi Shigeto Fukushima Yuichi Yamasaki Kazunori Kataoka Kanjiro Miyata Source Type: research